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Early physical and psycho-educational rehabilitation in patients with coronary artery bypass grafting: A randomized controlled trial

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@article{7a55b24540d8428cb13796651fcc0925,
title = "Early physical and psycho-educational rehabilitation in patients with coronary artery bypass grafting: A randomized controlled trial",
abstract = "OBJECTIVES: Rehabilitation of patients following coronary artery bypass grafting (CABG) has been widely studied; however, research into early rehabilitation after CABG is sparse. The aim of this trial was to assess the impact of early rehabilitation, compared with usual care in patients following CABG.DESIGN: Randomized controlled trial.PATIENTS: A total of 326 patients treated with CABG.METHODS: Patients treated with CABG were randomized 1:1 to 4 weeks of comprehensive early rehabilitation or usual care. The primary outcome was the Six Minute Walk Test (6MWT). Secondary outcomes were mental health and physical activity (Medical Outcome Study Short Form; SF-12); anxiety and depression (Hospital Anxiety and Depression Scale; HADS); physical and emotional scores; sleep (Pittsburgh Sleep Quality Index; PSQI); pain ({\"O}rebro Musculoskeletal Screening Questionnaire; {\"O}MSQ) and muscle endurance (Sit-To-Stand test).RESULTS: Sixteen patients dropped out. No significant differences between groups in the primary outcome (6MWT) were found after 4 weeks (p = 0.27). For secondary outcomes the odds ratio of HADS-D ≥ 8 decreased in favour of the experimental intervention (p = 0.04). There was non-adherence to parts of the intervention. Per-protocol analysis showed differences between groups for the 6MWT (p = 0.02) and the Sit-To-Stand test (p = 0.046).CONCLUSION: In general, the intervention had no effect on the 6MWT, or secondary outcomes, except for depressive symptoms. However, in adherent participants, the intervention had a positive effect for the primary and several secondary outcomes.",
keywords = "Coronary artery bypass grafting, Early rehabilitation, Phase 1 rehabilitation, Physical exercise, Psycho-education, Rehabilitation post-CABG, Humans, Male, Coronary Artery Bypass/methods, Female, Aged, Outcome Assessment, Health Care/methods, Exercise Therapy/methods",
author = "H{\o}jskov, {Ida Elisabeth} and Philips Moons and Ingrid Egerod and Olsen, {Peter Skov} and Thygesen, {Lau Caspar} and Hansen, {Niels Viggo} and {La Cour}, S{\o}ren and Bech, {Krisitna Hindhede} and Britt Borregaard and Christian Gluud and Per Winkel and Jane Lindschou and {Kikkenborg Berg}, Selina",
year = "2019",
month = jan,
day = "1",
doi = "10.2340/16501977-2499",
language = "English",
volume = "51",
pages = "136--143",
journal = "Journal of Rehabilitation Medicine",
issn = "1650-1977",
publisher = "Stiftelsen Rehabiliteringsinformation",
number = "2",

}

RIS

TY - JOUR

T1 - Early physical and psycho-educational rehabilitation in patients with coronary artery bypass grafting

T2 - A randomized controlled trial

AU - Højskov, Ida Elisabeth

AU - Moons, Philips

AU - Egerod, Ingrid

AU - Olsen, Peter Skov

AU - Thygesen, Lau Caspar

AU - Hansen, Niels Viggo

AU - La Cour, Søren

AU - Bech, Krisitna Hindhede

AU - Borregaard, Britt

AU - Gluud, Christian

AU - Winkel, Per

AU - Lindschou, Jane

AU - Kikkenborg Berg, Selina

PY - 2019/1/1

Y1 - 2019/1/1

N2 - OBJECTIVES: Rehabilitation of patients following coronary artery bypass grafting (CABG) has been widely studied; however, research into early rehabilitation after CABG is sparse. The aim of this trial was to assess the impact of early rehabilitation, compared with usual care in patients following CABG.DESIGN: Randomized controlled trial.PATIENTS: A total of 326 patients treated with CABG.METHODS: Patients treated with CABG were randomized 1:1 to 4 weeks of comprehensive early rehabilitation or usual care. The primary outcome was the Six Minute Walk Test (6MWT). Secondary outcomes were mental health and physical activity (Medical Outcome Study Short Form; SF-12); anxiety and depression (Hospital Anxiety and Depression Scale; HADS); physical and emotional scores; sleep (Pittsburgh Sleep Quality Index; PSQI); pain (Örebro Musculoskeletal Screening Questionnaire; ÖMSQ) and muscle endurance (Sit-To-Stand test).RESULTS: Sixteen patients dropped out. No significant differences between groups in the primary outcome (6MWT) were found after 4 weeks (p = 0.27). For secondary outcomes the odds ratio of HADS-D ≥ 8 decreased in favour of the experimental intervention (p = 0.04). There was non-adherence to parts of the intervention. Per-protocol analysis showed differences between groups for the 6MWT (p = 0.02) and the Sit-To-Stand test (p = 0.046).CONCLUSION: In general, the intervention had no effect on the 6MWT, or secondary outcomes, except for depressive symptoms. However, in adherent participants, the intervention had a positive effect for the primary and several secondary outcomes.

AB - OBJECTIVES: Rehabilitation of patients following coronary artery bypass grafting (CABG) has been widely studied; however, research into early rehabilitation after CABG is sparse. The aim of this trial was to assess the impact of early rehabilitation, compared with usual care in patients following CABG.DESIGN: Randomized controlled trial.PATIENTS: A total of 326 patients treated with CABG.METHODS: Patients treated with CABG were randomized 1:1 to 4 weeks of comprehensive early rehabilitation or usual care. The primary outcome was the Six Minute Walk Test (6MWT). Secondary outcomes were mental health and physical activity (Medical Outcome Study Short Form; SF-12); anxiety and depression (Hospital Anxiety and Depression Scale; HADS); physical and emotional scores; sleep (Pittsburgh Sleep Quality Index; PSQI); pain (Örebro Musculoskeletal Screening Questionnaire; ÖMSQ) and muscle endurance (Sit-To-Stand test).RESULTS: Sixteen patients dropped out. No significant differences between groups in the primary outcome (6MWT) were found after 4 weeks (p = 0.27). For secondary outcomes the odds ratio of HADS-D ≥ 8 decreased in favour of the experimental intervention (p = 0.04). There was non-adherence to parts of the intervention. Per-protocol analysis showed differences between groups for the 6MWT (p = 0.02) and the Sit-To-Stand test (p = 0.046).CONCLUSION: In general, the intervention had no effect on the 6MWT, or secondary outcomes, except for depressive symptoms. However, in adherent participants, the intervention had a positive effect for the primary and several secondary outcomes.

KW - Coronary artery bypass grafting

KW - Early rehabilitation

KW - Phase 1 rehabilitation

KW - Physical exercise

KW - Psycho-education

KW - Rehabilitation post-CABG

KW - Humans

KW - Male

KW - Coronary Artery Bypass/methods

KW - Female

KW - Aged

KW - Outcome Assessment, Health Care/methods

KW - Exercise Therapy/methods

UR - http://www.scopus.com/inward/record.url?scp=85060944447&partnerID=8YFLogxK

U2 - 10.2340/16501977-2499

DO - 10.2340/16501977-2499

M3 - Journal article

C2 - 30483722

VL - 51

SP - 136

EP - 143

JO - Journal of Rehabilitation Medicine

JF - Journal of Rehabilitation Medicine

SN - 1650-1977

IS - 2

ER -

ID: 56081059