Dual use of antifungals in medicine and agriculture: How do we help prevent resistance developing in human pathogens?

Paul E Verweij; Maiken C Arendrup; Ana Alastruey-Izquierdo; Jeremy A W Gold; Shawn R Lockhart; Tom Chiller; P Lewis White

doi:10.1016/j.drup.2022.100885

Dual use of antifungals in medicine and agriculture: How do we help prevent resistance developing in human pathogens?

Paul E Verweij^*, Maiken C Arendrup, Ana Alastruey-Izquierdo, Jeremy A W Gold, Shawn R Lockhart, Tom Chiller, P Lewis White

^*Corresponding author af dette arbejde

Afdeling for Klinisk Mikrobiologi

Abstract

Azole resistance in Aspergillus fumigatus is a One Health resistance threat, where azole fungicide exposure compromises the efficacy of medical azoles. The use of the recently authorized fungicide ipflufenoquin, which shares its mode-of-action with a new antifungal olorofim, underscores the need for risk assessment for dual use of antifungals.

Originalsprog	Engelsk
Artikelnummer	100885
Tidsskrift	Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Vol/bind	65
Sider (fra-til)	1-4
Antal sider	4
ISSN	1368-7646
DOI	https://doi.org/10.1016/j.drup.2022.100885
Status	Udgivet - dec. 2022

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10.1016/j.drup.2022.100885

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Verweij, P. E., Arendrup, M. C., Alastruey-Izquierdo, A., Gold, J. A. W., Lockhart, S. R., Chiller, T., & White, P. L. (2022). Dual use of antifungals in medicine and agriculture: How do we help prevent resistance developing in human pathogens? Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 65, 1-4. Artikel 100885. https://doi.org/10.1016/j.drup.2022.100885

Dual use of antifungals in medicine and agriculture: How do we help prevent resistance developing in human pathogens? / Verweij, Paul E; Arendrup, Maiken C; Alastruey-Izquierdo, Ana et al.
I: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, Bind 65, 100885, 12.2022, s. 1-4.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Verweij, PE, Arendrup, MC, Alastruey-Izquierdo, A, Gold, JAW, Lockhart, SR, Chiller, T & White, PL 2022, 'Dual use of antifungals in medicine and agriculture: How do we help prevent resistance developing in human pathogens?', Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, bind 65, 100885, s. 1-4. https://doi.org/10.1016/j.drup.2022.100885

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abstract = "Azole resistance in Aspergillus fumigatus is a One Health resistance threat, where azole fungicide exposure compromises the efficacy of medical azoles. The use of the recently authorized fungicide ipflufenoquin, which shares its mode-of-action with a new antifungal olorofim, underscores the need for risk assessment for dual use of antifungals.",

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AU - Chiller, Tom

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Dual use of antifungals in medicine and agriculture: How do we help prevent resistance developing in human pathogens?

Abstract

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