Dose-ranging evaluation of intravitreal siRNA PF-04523655 for diabetic macular edema (the DEGAS study)

Quan Dong Nguyen, Ronald A Schachar, Chudy I Nduaka, Marvin Sperling, Anthony S Basile, Karen J Klamerus, Katherine Chi-Burris, Eric Yan, Dario A Paggiarino, Irit Rosenblatt, Roger Aitchison, Shai S Erlich, DEGAS Clinical Study Group

86 Citationer (Scopus)

Abstract

To evaluate the safety and efficacy of three doses of PF-04523655, a 19-nucleotide methylated double stranded siRNA targeting the RTP801 gene, for the treatment of diabetic macular edema (DME) compared to focal/grid laser photocoagulation.
OriginalsprogEngelsk
TidsskriftInvestigative ophthalmology & visual science
Vol/bind53
Udgave nummer12
Sider (fra-til)7666-74
Antal sider9
ISSN0146-0404
DOI
StatusUdgivet - 2012

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