Dose-dependent anti-inflammatory effect of inhaled mometasone furoate/formoterol in subjects with asthma

Hendrik Nolte, Ian Pavord, Vibeke Backer, Sheldon Spector, Tulin Shekar, Davis Gates, Parameswaran Nair, Frederick Hargreave

27 Citationer (Scopus)

Abstrakt

A well-controlled study in patients with allergic asthma was warranted to assess dose-dependency between fractional concentration of exhaled nitric oxide (FeNO) and sputum eosinophils to a combination of an inhaled corticosteroid plus a long-acting β2-agonist. We sought to characterize the dose-dependency of mometasone furoate/formoterol (MF/F) using FeNO and sputum eosinophil percentage as surrogates of airway inflammation in subjects with allergic asthma.
OriginalsprogEngelsk
TidsskriftRespiratory medicine
Vol/bind107
Udgave nummer5
Sider (fra-til)656-64
Antal sider9
ISSN0954-6111
DOI
StatusUdgivet - maj 2013

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