Distinct transthyretin oxidation isoform profile in spinal fluid from patients with Alzheimer's disease and mild cognitive impairment

Keyphrases

• Alzheimer's Disease 100%
• Mild Cognitive Impairment 100%
• Transthyretin 100%
• Spinal Fluid 100%
• Cerebrospinal Fluid 46%
• Idiopathic Normal Pressure Hydrocephalus (iNPH) 30%
• Healthy Controls 23%
• Diagnostic Information 23%
• Neurodegenerative Diseases 15%
• Cerebrospinal Fluid Samples 15%
• Isoform Distribution 15%
• High Risk 7%
• Disease Activity 7%
• Patients with Dementia 7%
• New Drugs 7%
• Patient-controlled 7%
• Oxidative Stress 7%
• Mass Spectrometry Methods 7%
• Dementia Symptoms 7%
• High Protein 7%
• Oxidative Modification 7%
• Disease Monitoring 7%
• Cerebrospinal Fluid Biomarkers 7%
• Sample Handling 7%
• Cysteine Residues 7%
• Alzheimer's Disease Patient 7%
• Phosphorylated tau 7%
• τ-value 7%
• Alzheimer's Disease Biomarkers 7%
• Amyloid-β Peptide 7%
• Affinity Purification-mass Spectrometry (AP-MS) 7%
• Uniform Guidelines 7%
• S-glutathionylation 7%
• Study Monitoring 7%
• In Vivo Oxidation 7%
• Free Oxidation 7%

Biochemistry, Genetics and Molecular Biology

• Isoform 100%
• Liquid 100%
• Alpha Oxidation 100%
• Transthyretin 100%
• Tau 23%
• Amyloid 15%
• Prospective Study 7%
• Oxidative Stress 7%
• Cysteine 7%
• Mass Spectrometry 7%
• Antibody Affinity 7%
• S-Glutathionylation 7%

Neuroscience

• Alzheimer's Disease 100%
• Mild Cognitive Impairment 100%
• Transthyretin 100%
• Normal Pressure Hydrocephalus 30%
• Neurodegenerative Disorder 15%
• Amyloid 15%
• In Vivo 7%
• In Vitro 7%
• Oxidative Stress 7%
• Mass Spectrometry 7%
• Cysteine 7%
• Antibody Affinity 7%