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Region Hovedstaden - en del af Københavns Universitetshospital
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Display of wasp venom allergens on the cell surface of Saccharomyces cerevisiae

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Vis graf over relationer
Yeast surface display is a technique, where the proteins of interest are expressed as fusions with yeast surface proteins and thus remain attached to the yeast cell wall after expression. Our purpose was to study whether allergens expressed on the cell surface of baker's yeast Saccharomyces cerevisiae preserve their native allergenic properties and whether the yeast native surface glycoproteins interfere with IgE binding. We chose to use the major allergens from the common wasp Vespula vulgaris venom: phospholipase A1, hyaluronidase and antigen 5 as the model.
OriginalsprogEngelsk
TidsskriftMicrobial Cell Factories
Vol/bind9
Sider (fra-til)74
ISSN1475-2859
DOI
StatusUdgivet - 1 jan. 2010

ID: 32164960