Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis

T Edholm, M Degerblad, P Grybäck, Linda Maria Hilsted, Jens Møller Holst, H Jacobsson, S Efendic, P T Schmidt, P M Hellström

132 Citationer (Scopus)

Abstract

Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are major incretins with important effects on glucoregulatory functions. The aim of this study was to investigate effects of GIP and GLP-1 on gastric emptying and appetite after a mixed meal, and effects on insulin secretion and glucose disposal in humans.
OriginalsprogEngelsk
TidsskriftNeurogastroenterology and Motility
Vol/bind22
Udgave nummer11
Sider (fra-til)1191-200, e315
ISSN1350-1925
DOI
StatusUdgivet - 1 nov. 2010

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