Dietary factors impact on the association between CTSS variants and obesity related traits

Henri Hooton, Lars Henrik Ängquist, Claus Holst, Jorg Hager, Francis Rousseau, Rikke D Hansen, Anne Tjønneland, Nina Roswall, Daphne L van der A, Kim Overvad, Marianne Uhre Jakobsen, Heiner Boeing, Karina Meidtner, Domenico Palli, Giovanna Masala, Nabila Bouatia-Naji, Wim H M Saris, Edith J M Feskens, Nicolas J Wareham, Karani S VimaleswaranDominique Langin, Ruth J F Loos, Thorkild I A Sørensen, Karine Clément

    11 Citationer (Scopus)

    Abstract

    Cathepsin S, a protein coded by the CTSS gene, is implicated in adipose tissue biology--this protein enhances adipose tissue development. Our hypothesis is that common variants in CTSS play a role in body weight regulation and in the development of obesity and that these effects are influenced by dietary factors--increased by high protein, glycemic index and energy diets.
    OriginalsprogEngelsk
    TidsskriftP L o S One
    Vol/bind7
    Udgave nummer7
    Sider (fra-til)e40394
    ISSN1932-6203
    DOI
    StatusUdgivet - 2012

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