Dianicline, a novel α4β2 nicotinic acetylcholine receptor partial agonist, for smoking cessation: a randomized placebo-controlled clinical trial

Serena Tonstad; Ingar Holme; Philip Tønnesen

doi:10.1093/ntr/ntq191

Dianicline, a novel α4β2 nicotinic acetylcholine receptor partial agonist, for smoking cessation: a randomized placebo-controlled clinical trial

Serena Tonstad, Ingar Holme, Philip Tønnesen

Lungesygdomme HGH

19 Citationer (Scopus)

Abstract

Dianicline is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of drugs that includes varenicline and cytisine. Varenicline is efficacious for smoking cessation, while cytisine has not been studied systematically. The efficacy of dianicline has not been previously tested in an adequately powered study.

Originalsprog	Engelsk
Tidsskrift	Nicotine & Tobacco Research
Vol/bind	13
Udgave nummer	1
Sider (fra-til)	1-6
Antal sider	6
ISSN	1462-2203
DOI	https://doi.org/10.1093/ntr/ntq191
Status	Udgivet - 1 jan. 2011

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AU - Holme, Ingar

AU - Tønnesen, Philip

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N2 - Dianicline is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of drugs that includes varenicline and cytisine. Varenicline is efficacious for smoking cessation, while cytisine has not been studied systematically. The efficacy of dianicline has not been previously tested in an adequately powered study.

AB - Dianicline is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of drugs that includes varenicline and cytisine. Varenicline is efficacious for smoking cessation, while cytisine has not been studied systematically. The efficacy of dianicline has not been previously tested in an adequately powered study.

KW - Adult

KW - Azepines

KW - Double-Blind Method

KW - Female

KW - Heterocyclic Compounds with 4 or More Rings

KW - Humans

KW - Male

KW - Middle Aged

KW - Nicotinic Agonists

KW - Placebos

KW - Receptors, Nicotinic

KW - Smoking

KW - Smoking Cessation

UR - https://www.scopus.com/pages/publications/78650355219

U2 - 10.1093/ntr/ntq191

DO - 10.1093/ntr/ntq191

M3 - Journal article

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SN - 1462-2203

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EP - 6

JO - Nicotine & Tobacco Research

JF - Nicotine & Tobacco Research

IS - 1

ER -

Dianicline, a novel α4β2 nicotinic acetylcholine receptor partial agonist, for smoking cessation: a randomized placebo-controlled clinical trial

Abstract

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