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Region Hovedstaden - en del af Københavns Universitetshospital
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Diagnosis of central disorders of hypersomnolence: A reappraisal by European experts

Publikation: Bidrag til tidsskriftReviewForskningpeer review

DOI

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  • Gert Jan Lammers
  • Claudio L A Bassetti
  • Leja Dolenc-Groselj
  • Poul J Jennum
  • Ulf Kallweit
  • Ramin Khatami
  • Michel Lecendreux
  • Mauro Manconi
  • Geert Mayer
  • Markku Partinen
  • Giuseppe Plazzi
  • Paul J Reading
  • Joan Santamaria
  • Karel Sonka
  • Yves Dauvilliers
Vis graf over relationer

The aim of this European initiative is to facilitate a structured discussion to improve the next edition of the International Classification of Sleep Disorders (ICSD), particularly the chapter on central disorders of hypersomnolence. The ultimate goal for a sleep disorders classification is to be based on the underlying neurobiological causes of the disorders with clear implication for treatment or, ideally, prevention and or healing. The current ICSD classification, published in 2014, inevitably has important shortcomings, largely reflecting the lack of knowledge about the precise neurobiological mechanisms underlying the majority of sleep disorders we currently delineate. Despite a clear rationale for the present structure, there remain important limitations that make it difficult to apply in routine clinical practice. Moreover, there are indications that the current structure may even prevent us from gaining relevant new knowledge to better understand certain sleep disorders and their neurobiological causes. We suggest the creation of a new consistent, complaint driven, hierarchical classification for central disorders of hypersomnolence; containing levels of certainty, and giving diagnostic tests, particularly the MSLT, a weighting based on its specificity and sensitivity in the diagnostic context. We propose and define three diagnostic categories (with levels of certainty): 1/"Narcolepsy" 2/"Idiopathic hypersomnia", 3/"Idiopathic excessive sleepiness" (with subtypes).

OriginalsprogEngelsk
Artikelnummer101306
TidsskriftSleep Medicine Reviews
Vol/bind52
Sider (fra-til)101306
ISSN1087-0792
DOI
StatusUdgivet - aug. 2020

Bibliografisk note

Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.

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