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Development of depression in patients with oral cavity cancer: a systematic review

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@article{d01141210da94349a00f45339ab9bb88,
title = "Development of depression in patients with oral cavity cancer: a systematic review",
abstract = "BACKGROUND: The incidence of oral cancer is approximately 300,000 patients annually. A cancer diagnosis and treatment affect both physical and mental issues.OBJECTIVES: The aim of this systematic review was to examine the development of depression in patients who have been treated for oral squamous cell carcinoma (OSCC).MATERIAL AND METHODS: PubMed and EMBASE were systematically searched for studies addressing depression among patients treated for OSCC and published within the past ten years.RESULTS: We identified three studies comprising 528 patients (range: 75-349), primarily men (66-83%), treated for OSCC from Europe and India. Tumour stage, treatment modality, and scales used to evaluate depressive symptoms varied in the studies. The European studies showed that 28% of the patients experienced depressive symptoms on the Hospital Anxiety and Depression Scale (HADS) and a mean of 8.0 on depression in the Brief Symptom Inventory (BSI). The Indian study showed a significant increase (p Value < .001) from moderate to severe depressive symptoms on the Depression, Anxiety, and Stress Scale-21 (DASS-21). Conclusion and Significance: This systematic review showed that OSCC patients are at risk of developing depressive symptoms after treatment, though severity of symptoms varied. This knowledge could preferably be implemented in future follow-up regimes.",
keywords = "after treatment, depression, depressive symptoms, oral cavity cancer, oral squamous cell carcinoma, OSCC, Systematic review",
author = "Lansner, {Mira Westphal} and Jakobsen, {Kathrine Kronberg} and Jensen, {Jakob Schmidt} and Sandsten, {Karl Erik} and Christian Gr{\o}nh{\o}j and {von Buchwald}, Christian",
year = "2020",
month = oct,
doi = "10.1080/00016489.2020.1778785",
language = "English",
volume = "140",
pages = "876--881",
journal = "Acta Oto-Laryngologica",
issn = "0001-6489",
publisher = "Informa Healthcare",
number = "10",

}

RIS

TY - JOUR

T1 - Development of depression in patients with oral cavity cancer

T2 - a systematic review

AU - Lansner, Mira Westphal

AU - Jakobsen, Kathrine Kronberg

AU - Jensen, Jakob Schmidt

AU - Sandsten, Karl Erik

AU - Grønhøj, Christian

AU - von Buchwald, Christian

PY - 2020/10

Y1 - 2020/10

N2 - BACKGROUND: The incidence of oral cancer is approximately 300,000 patients annually. A cancer diagnosis and treatment affect both physical and mental issues.OBJECTIVES: The aim of this systematic review was to examine the development of depression in patients who have been treated for oral squamous cell carcinoma (OSCC).MATERIAL AND METHODS: PubMed and EMBASE were systematically searched for studies addressing depression among patients treated for OSCC and published within the past ten years.RESULTS: We identified three studies comprising 528 patients (range: 75-349), primarily men (66-83%), treated for OSCC from Europe and India. Tumour stage, treatment modality, and scales used to evaluate depressive symptoms varied in the studies. The European studies showed that 28% of the patients experienced depressive symptoms on the Hospital Anxiety and Depression Scale (HADS) and a mean of 8.0 on depression in the Brief Symptom Inventory (BSI). The Indian study showed a significant increase (p Value < .001) from moderate to severe depressive symptoms on the Depression, Anxiety, and Stress Scale-21 (DASS-21). Conclusion and Significance: This systematic review showed that OSCC patients are at risk of developing depressive symptoms after treatment, though severity of symptoms varied. This knowledge could preferably be implemented in future follow-up regimes.

AB - BACKGROUND: The incidence of oral cancer is approximately 300,000 patients annually. A cancer diagnosis and treatment affect both physical and mental issues.OBJECTIVES: The aim of this systematic review was to examine the development of depression in patients who have been treated for oral squamous cell carcinoma (OSCC).MATERIAL AND METHODS: PubMed and EMBASE were systematically searched for studies addressing depression among patients treated for OSCC and published within the past ten years.RESULTS: We identified three studies comprising 528 patients (range: 75-349), primarily men (66-83%), treated for OSCC from Europe and India. Tumour stage, treatment modality, and scales used to evaluate depressive symptoms varied in the studies. The European studies showed that 28% of the patients experienced depressive symptoms on the Hospital Anxiety and Depression Scale (HADS) and a mean of 8.0 on depression in the Brief Symptom Inventory (BSI). The Indian study showed a significant increase (p Value < .001) from moderate to severe depressive symptoms on the Depression, Anxiety, and Stress Scale-21 (DASS-21). Conclusion and Significance: This systematic review showed that OSCC patients are at risk of developing depressive symptoms after treatment, though severity of symptoms varied. This knowledge could preferably be implemented in future follow-up regimes.

KW - after treatment

KW - depression

KW - depressive symptoms

KW - oral cavity cancer

KW - oral squamous cell carcinoma

KW - OSCC

KW - Systematic review

U2 - 10.1080/00016489.2020.1778785

DO - 10.1080/00016489.2020.1778785

M3 - Review

C2 - 32644847

VL - 140

SP - 876

EP - 881

JO - Acta Oto-Laryngologica

JF - Acta Oto-Laryngologica

SN - 0001-6489

IS - 10

ER -

ID: 60536536