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Determination of peripapillary vessel density in optic disc drusen using EDI-OCT and OCT angiography

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Lindberg, Anne-Sofie Wessel ; Dahl, Vedrana Andersen ; Karlesand, Isabelle ; Rueløkke, Lea Lybek ; Malmqvist, Lasse ; Hamann, Steffen. / Determination of peripapillary vessel density in optic disc drusen using EDI-OCT and OCT angiography. I: Experimental Eye Research. 2020 ; Bind 197. s. 108123.

Bibtex

@article{020dc04acbcb46afb1ae31df377be55e,
title = "Determination of peripapillary vessel density in optic disc drusen using EDI-OCT and OCT angiography",
abstract = "Optical coherence tomography angiography (OCTA) is a rapidly developing technique which generates angiographic images non-invasively. This study proposes a method to determine the vessel density in OCTA scans in general and especially the local peripapillary vessel density. The method produces vessel density heatmaps that contain information about the local vessel density. We apply the method in a small study to demonstrate its applicability and its potential to investigate the influence of local conditions on the vessel density. In the study, we combine information from enhanced depth imaging optical coherence tomography (EDI-OCT) about the location of optic disc drusen (ODD) with information from OCTA about the vessel density. We see a reduction in local peripapillary vessel density in peripapillary sections with a large volume of ODD.",
keywords = "Female, Fluorescein Angiography/methods, Fundus Oculi, Humans, Male, Microvessels/pathology, Nerve Fibers/pathology, Optic Disk/blood supply, Optic Disk Drusen, Retinal Vessels/pathology, Tomography, Optical Coherence/methods, Visual Acuity, Visual Fields",
author = "Lindberg, {Anne-Sofie Wessel} and Dahl, {Vedrana Andersen} and Isabelle Karlesand and Ruel{\o}kke, {Lea Lybek} and Lasse Malmqvist and Steffen Hamann",
note = "Copyright {\textcopyright} 2020 Elsevier Ltd. All rights reserved.",
year = "2020",
month = aug,
doi = "10.1016/j.exer.2020.108123",
language = "English",
volume = "197",
pages = "108123",
journal = "Experimental Eye Research",
issn = "0014-4835",
publisher = "Academic Press",

}

RIS

TY - JOUR

T1 - Determination of peripapillary vessel density in optic disc drusen using EDI-OCT and OCT angiography

AU - Lindberg, Anne-Sofie Wessel

AU - Dahl, Vedrana Andersen

AU - Karlesand, Isabelle

AU - Rueløkke, Lea Lybek

AU - Malmqvist, Lasse

AU - Hamann, Steffen

N1 - Copyright © 2020 Elsevier Ltd. All rights reserved.

PY - 2020/8

Y1 - 2020/8

N2 - Optical coherence tomography angiography (OCTA) is a rapidly developing technique which generates angiographic images non-invasively. This study proposes a method to determine the vessel density in OCTA scans in general and especially the local peripapillary vessel density. The method produces vessel density heatmaps that contain information about the local vessel density. We apply the method in a small study to demonstrate its applicability and its potential to investigate the influence of local conditions on the vessel density. In the study, we combine information from enhanced depth imaging optical coherence tomography (EDI-OCT) about the location of optic disc drusen (ODD) with information from OCTA about the vessel density. We see a reduction in local peripapillary vessel density in peripapillary sections with a large volume of ODD.

AB - Optical coherence tomography angiography (OCTA) is a rapidly developing technique which generates angiographic images non-invasively. This study proposes a method to determine the vessel density in OCTA scans in general and especially the local peripapillary vessel density. The method produces vessel density heatmaps that contain information about the local vessel density. We apply the method in a small study to demonstrate its applicability and its potential to investigate the influence of local conditions on the vessel density. In the study, we combine information from enhanced depth imaging optical coherence tomography (EDI-OCT) about the location of optic disc drusen (ODD) with information from OCTA about the vessel density. We see a reduction in local peripapillary vessel density in peripapillary sections with a large volume of ODD.

KW - Female

KW - Fluorescein Angiography/methods

KW - Fundus Oculi

KW - Humans

KW - Male

KW - Microvessels/pathology

KW - Nerve Fibers/pathology

KW - Optic Disk/blood supply

KW - Optic Disk Drusen

KW - Retinal Vessels/pathology

KW - Tomography, Optical Coherence/methods

KW - Visual Acuity

KW - Visual Fields

U2 - 10.1016/j.exer.2020.108123

DO - 10.1016/j.exer.2020.108123

M3 - Journal article

C2 - 32619579

VL - 197

SP - 108123

JO - Experimental Eye Research

JF - Experimental Eye Research

SN - 0014-4835

ER -

ID: 61986508