Determinants of serum tryptase in a general population: the relationship of serum tryptase to obesity and asthma

R V Fenger, A Linneberg, C Vidal, L Vizcaino, Lise-Lotte Husemoen, M Aadahl, A Gonzalez-Quintela

    44 Citationer (Scopus)

    Abstract

    Recent studies indicate that mast cells are more abundant in the obese state. Total serum tryptase (ST) is a marker of mast cell numbers or activity. Since obesity and asthma have been consistently linked in epidemiological studies, a possible higher mast cell activity in obesity could be a factor between the two conditions. The aim of this study was to investigate determinants of ST and whether a potential association between obesity and allergic respiratory disease would be influenced by levels of ST in obese persons.
    OriginalsprogEngelsk
    TidsskriftInternational Archives of Allergy and Immunology
    Vol/bind157
    Udgave nummer2
    Sider (fra-til)151-8
    Antal sider8
    ISSN1018-2438
    DOI
    StatusUdgivet - 2012

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