@article{424a1df319a4461c8921e192771376a3,
title = "Design, history and results of the Thiazolidinedione Intervention with vitamin D Evaluation (TIDE) randomised controlled trial",
abstract = "AIMS/OBJECTIVE: Conflicting data regarding cardiovascular effects of thiazolidinediones (TZDs) and extra-skeletal effects of vitamin D supported the need for a definitive trial. The Thiazolidinedione Intervention with vitamin D Evaluation (TIDE) trial aimed to assess the effects of TZDs (rosiglitazone and pioglitazone) on cardiovascular outcomes and the effects of vitamin D (cholecalciferol) on cancers and mortality.",
keywords = "Aged, Cardiovascular Diseases, Cholecalciferol, Combined Modality Therapy, Diabetes Mellitus, Type 2, Dietary Supplements, Dose-Response Relationship, Drug, Double-Blind Method, Early Termination of Clinical Trials, Female, Humans, Hypoglycemic Agents, Incidence, Male, Middle Aged, Neoplasms, Risk Factors, Thiazolidinediones",
author = "Z Punthakee and J Bosch and G Dagenais and Diaz, {Ricardo Gredilla} and R Holman and Probstfield, {J L} and A Ramachandran and Riddle, {M C} and Ryd{\'e}n, {L E} and B Zinman and R Afzal and S Yusuf and Gerstein, {H C} and {TIDE Trial Investigators} and Torp-Pedersen, {Christian Tobias}",
year = "2012",
month = jan,
doi = "10.1007/s00125-011-2357-4",
language = "English",
volume = "55",
pages = "36--45",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer Science and Business Media Deutschland GmbH",
number = "1",
}