Descending pain modulation and its interaction with peripheral sensitization following sustained isometric muscle contraction in fibromyalgia

H-Y Ge; Hongling Nie; Thomas Graven-Nielsen; B Danneskiold-Samsøe; Lars Arendt-Nielsen

doi:10.1016/j.ejpain.2011.06.008

Descending pain modulation and its interaction with peripheral sensitization following sustained isometric muscle contraction in fibromyalgia

H-Y Ge, Hongling Nie, Thomas Graven-Nielsen, B Danneskiold-Samsøe, Lars Arendt-Nielsen

Parker Instituttet

43 Citationer (Scopus)

Abstract

Sustained isometric muscle contraction (fatiguing contraction) recruits segmental and/or extrasegmental descending inhibition in healthy subjects but not in fibromyalgia (FM). We hypothesized that fatiguing contraction may shift descending pain modulation from inhibition towards facilitation and that the effect of descending pain modulation be dependent on peripheral muscle pain sensitivity.

Originalsprog	Engelsk
Tidsskrift	European Journal of Pain
Vol/bind	16
Udgave nummer	2
Sider (fra-til)	196-203
Antal sider	8
ISSN	1090-3801
DOI	https://doi.org/10.1016/j.ejpain.2011.06.008
Status	Udgivet - 2012

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title = "Descending pain modulation and its interaction with peripheral sensitization following sustained isometric muscle contraction in fibromyalgia",

abstract = "Sustained isometric muscle contraction (fatiguing contraction) recruits segmental and/or extrasegmental descending inhibition in healthy subjects but not in fibromyalgia (FM). We hypothesized that fatiguing contraction may shift descending pain modulation from inhibition towards facilitation and that the effect of descending pain modulation be dependent on peripheral muscle pain sensitivity.",

keywords = "Adolescent, Adult, Aged, Chronic Pain, Female, Fibromyalgia, Humans, Isometric Contraction, Middle Aged, Neural Inhibition, Nociceptors, Pain Threshold, Young Adult",

author = "H-Y Ge and Hongling Nie and Thomas Graven-Nielsen and B Danneskiold-Sams{\o}e and Lars Arendt-Nielsen",

note = "{\textcopyright} 2011 European Federation of International Association for the Study of Pain Chapters.",

year = "2012",

doi = "10.1016/j.ejpain.2011.06.008",

language = "English",

volume = "16",

pages = "196--203",

journal = "European Journal of Pain",

issn = "1090-3801",

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TY - JOUR

T1 - Descending pain modulation and its interaction with peripheral sensitization following sustained isometric muscle contraction in fibromyalgia

AU - Ge, H-Y

AU - Nie, Hongling

AU - Graven-Nielsen, Thomas

AU - Danneskiold-Samsøe, B

AU - Arendt-Nielsen, Lars

PY - 2012

Y1 - 2012

N2 - Sustained isometric muscle contraction (fatiguing contraction) recruits segmental and/or extrasegmental descending inhibition in healthy subjects but not in fibromyalgia (FM). We hypothesized that fatiguing contraction may shift descending pain modulation from inhibition towards facilitation and that the effect of descending pain modulation be dependent on peripheral muscle pain sensitivity.

AB - Sustained isometric muscle contraction (fatiguing contraction) recruits segmental and/or extrasegmental descending inhibition in healthy subjects but not in fibromyalgia (FM). We hypothesized that fatiguing contraction may shift descending pain modulation from inhibition towards facilitation and that the effect of descending pain modulation be dependent on peripheral muscle pain sensitivity.

KW - Adolescent

KW - Adult

KW - Aged

KW - Chronic Pain

KW - Female

KW - Fibromyalgia

KW - Humans

KW - Isometric Contraction

KW - Middle Aged

KW - Neural Inhibition

KW - Nociceptors

KW - Pain Threshold

KW - Young Adult

UR - https://www.scopus.com/pages/publications/84871442925

U2 - 10.1016/j.ejpain.2011.06.008

DO - 10.1016/j.ejpain.2011.06.008

M3 - Journal article

C2 - 22323372

SN - 1090-3801

VL - 16

SP - 196

EP - 203

JO - European Journal of Pain

JF - European Journal of Pain

IS - 2

ER -

Descending pain modulation and its interaction with peripheral sensitization following sustained isometric muscle contraction in fibromyalgia

Abstract

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