Descending pain modulation and its interaction with peripheral sensitization following sustained isometric muscle contraction in fibromyalgia

H-Y Ge, Hongling Nie, Thomas Graven-Nielsen, B Danneskiold-Samsøe, Lars Arendt-Nielsen

34 Citationer (Scopus)

Abstrakt

Sustained isometric muscle contraction (fatiguing contraction) recruits segmental and/or extrasegmental descending inhibition in healthy subjects but not in fibromyalgia (FM). We hypothesized that fatiguing contraction may shift descending pain modulation from inhibition towards facilitation and that the effect of descending pain modulation be dependent on peripheral muscle pain sensitivity.
OriginalsprogEngelsk
TidsskriftEuropean Journal of Pain
Vol/bind16
Udgave nummer2
Sider (fra-til)196-203
Antal sider8
ISSN1090-3801
DOI
StatusUdgivet - 2012

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