Der er forandringer i hjernens ledningsbaner ved skizofreni

Bjørn H Ebdrup; Nana Skovgaard; Jayachandra M Raghava; Birte Glenthøj

Der er forandringer i hjernens ledningsbaner ved skizofreni

Bjørn H Ebdrup, Nana Skovgaard, Jayachandra M Raghava, Birte Glenthøj

Abstract

Schizophrenia is a brain disorder characterized by fundamental changes in thinking and beliefs. Alterations in white matter integrity may underlie the characteristic psychotic symptoms. This review focuses on diffusion tensor imaging studies in schizophrenia patients. Overall, schizophrenia appears to be associated with white matter deficits particularly in the fronto-temporal connections. To dissect potential medication effects from myelination deficits related to symptoms, longitudinal studies in initially antipsychotic-naive first-episode patients with schizophrenia are needed.

Bidragets oversatte titel	White matter alterations in schizophrenia.
Originalsprog	Dansk
Artikelnummer	176
Tidsskrift	Ugeskrift for læger [online]
Vol/bind	176
Udgave nummer	46
Sider (fra-til)	2-6
Antal sider	5
ISSN	1603-6824
Status	Udgivet - 10 nov. 2014

Citationsformater

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AU - Ebdrup, Bjørn H

AU - Skovgaard, Nana

AU - Raghava, Jayachandra M

AU - Glenthøj, Birte

PY - 2014/11/10

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N2 - Schizophrenia is a brain disorder characterized by fundamental changes in thinking and beliefs. Alterations in white matter integrity may underlie the characteristic psychotic symptoms. This review focuses on diffusion tensor imaging studies in schizophrenia patients. Overall, schizophrenia appears to be associated with white matter deficits particularly in the fronto-temporal connections. To dissect potential medication effects from myelination deficits related to symptoms, longitudinal studies in initially antipsychotic-naive first-episode patients with schizophrenia are needed.

AB - Schizophrenia is a brain disorder characterized by fundamental changes in thinking and beliefs. Alterations in white matter integrity may underlie the characteristic psychotic symptoms. This review focuses on diffusion tensor imaging studies in schizophrenia patients. Overall, schizophrenia appears to be associated with white matter deficits particularly in the fronto-temporal connections. To dissect potential medication effects from myelination deficits related to symptoms, longitudinal studies in initially antipsychotic-naive first-episode patients with schizophrenia are needed.

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Der er forandringer i hjernens ledningsbaner ved skizofreni

Abstract

Fingeraftryk

Citationsformater