Depression and anxiety in adult patients with epilepsy

There is a bidirectional association between epilepsy and depression and anxiety which are more prevalent in temporal lobe epilepsy and medically intractable epilepsy and are underdiagnosed. Many factors determine the occurrence of psychiatric symptoms. It is recommended that The Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) and Generalised Anxiety Disorder Assessment (GAD-7) are employed for screening. This review finds that systematic screening should be routinely performed and treatment should be carried out in a formalized collaboration between neurologist, psychiatrist and psychologist.