Den endokrine og metaboliske kobling mellem COVID-19, diabetes og fedme

Nina Weis; Kristina Thorsteinsson; Christoffer Martinussen; Sten Madsbad

Den endokrine og metaboliske kobling mellem COVID-19, diabetes og fedme

Nina Weis, Kristina Thorsteinsson, Christoffer Martinussen, Sten Madsbad

4 Citationer (Scopus)

Abstract

Coronavirus disease 2019 (COVID-19) is caused by infection with severe acute respiratory syndrome corona virus 2. High age, hypertension, diabetes, and obesity are risk factors for severe COVID-19 with increased mortality. In this review, we discuss potential mechanisms by which diabetes and obesity modulate the host viral interactions and host-immune response. Glucose levels should be monitored rigorously, and patient-tailored aggressive treatment of hyperglycaemia is recommended, often with the use of insulin. Persons with diabetes and obesity are susceptible to severe outcomes from COVID-19.

Bidragets oversatte titel	The endocrine and metabolic link between COVID-19, diabetes and obesity
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	182
Udgave nummer	29
ISSN	0041-5782
Status	Udgivet - 13 jul. 2020

Emneord

Betacoronavirus
COVID-19
Coronavirus Infections/complications
Diabetes Mellitus/metabolism
Endocrine System
Host Microbial Interactions
Humans
Hyperglycemia/drug therapy
Insulin/therapeutic use
Obesity/complications
Pandemics
Pneumonia, Viral/complications
Risk Factors
SARS-CoV-2

Citationsformater

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abstract = "Coronavirus disease 2019 (COVID-19) is caused by infection with severe acute respiratory syndrome corona virus 2. High age, hypertension, diabetes, and obesity are risk factors for severe COVID-19 with increased mortality. In this review, we discuss potential mechanisms by which diabetes and obesity modulate the host viral interactions and host-immune response. Glucose levels should be monitored rigorously, and patient-tailored aggressive treatment of hyperglycaemia is recommended, often with the use of insulin. Persons with diabetes and obesity are susceptible to severe outcomes from COVID-19.",

keywords = "Betacoronavirus, COVID-19, Coronavirus Infections/complications, Diabetes Mellitus/metabolism, Endocrine System, Host Microbial Interactions, Humans, Hyperglycemia/drug therapy, Insulin/therapeutic use, Obesity/complications, Pandemics, Pneumonia, Viral/complications, Risk Factors, SARS-CoV-2",

author = "Nina Weis and Kristina Thorsteinsson and Christoffer Martinussen and Sten Madsbad",

year = "2020",

month = jul,

day = "13",

language = "Dansk",

volume = "182",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

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TY - JOUR

T1 - Den endokrine og metaboliske kobling mellem COVID-19, diabetes og fedme

AU - Weis, Nina

AU - Thorsteinsson, Kristina

AU - Martinussen, Christoffer

AU - Madsbad, Sten

PY - 2020/7/13

Y1 - 2020/7/13

N2 - Coronavirus disease 2019 (COVID-19) is caused by infection with severe acute respiratory syndrome corona virus 2. High age, hypertension, diabetes, and obesity are risk factors for severe COVID-19 with increased mortality. In this review, we discuss potential mechanisms by which diabetes and obesity modulate the host viral interactions and host-immune response. Glucose levels should be monitored rigorously, and patient-tailored aggressive treatment of hyperglycaemia is recommended, often with the use of insulin. Persons with diabetes and obesity are susceptible to severe outcomes from COVID-19.

AB - Coronavirus disease 2019 (COVID-19) is caused by infection with severe acute respiratory syndrome corona virus 2. High age, hypertension, diabetes, and obesity are risk factors for severe COVID-19 with increased mortality. In this review, we discuss potential mechanisms by which diabetes and obesity modulate the host viral interactions and host-immune response. Glucose levels should be monitored rigorously, and patient-tailored aggressive treatment of hyperglycaemia is recommended, often with the use of insulin. Persons with diabetes and obesity are susceptible to severe outcomes from COVID-19.

KW - Betacoronavirus

KW - COVID-19

KW - Coronavirus Infections/complications

KW - Diabetes Mellitus/metabolism

KW - Endocrine System

KW - Host Microbial Interactions

KW - Humans

KW - Hyperglycemia/drug therapy

KW - Insulin/therapeutic use

KW - Obesity/complications

KW - Pandemics

KW - Pneumonia, Viral/complications

KW - Risk Factors

KW - SARS-CoV-2

M3 - Review

C2 - 32734864

SN - 0041-5782

VL - 182

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 29

ER -

Den endokrine og metaboliske kobling mellem COVID-19, diabetes og fedme

Abstract

Emneord

Fingeraftryk

Citationsformater