Den endokrine og metaboliske kobling mellem COVID-19, diabetes og fedme

Abstract

Coronavirus disease 2019 (COVID-19) is caused by infection with severe acute respiratory syndrome corona virus 2. High age, hypertension, diabetes, and obesity are risk factors for severe COVID-19 with increased mortality. In this review, we discuss potential mechanisms by which diabetes and obesity modulate the host viral interactions and host-immune response. Glucose levels should be monitored rigorously, and patient-tailored aggressive treatment of hyperglycaemia is recommended, often with the use of insulin. Persons with diabetes and obesity are susceptible to severe outcomes from COVID-19.

Bidragets oversatte titelThe endocrine and metabolic link between COVID-19, diabetes and obesity
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind182
Udgave nummer29
ISSN0041-5782
StatusUdgivet - 13 jul. 2020

Emneord

  • Betacoronavirus
  • COVID-19
  • Coronavirus Infections/complications
  • Diabetes Mellitus/metabolism
  • Endocrine System
  • Host Microbial Interactions
  • Humans
  • Hyperglycemia/drug therapy
  • Insulin/therapeutic use
  • Obesity/complications
  • Pandemics
  • Pneumonia, Viral/complications
  • Risk Factors
  • SARS-CoV-2

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