Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
E-pub ahead of print

Declining prevalence of cerebral palsy in children born at term in Denmark

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Nutritional screening of children and adolescents with cerebral palsy: a scoping review

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  2. Anti-dopamine D2 receptor antibodies in chronic tic disorders

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Specialist health care services use in a European cohort of infants born very preterm

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. A Nationwide Observational Study of Chlamydia trachomatis Infections in Denmark during the COVID-19 Pandemic

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Outcome of subsequent pregnancies in women with complete uterine rupture: A population-based case-control study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. First-trimester biomarkers and the risk of cerebral palsy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Cardiovascular function in 8- to 9-year-old singletons born after ART with frozen and fresh embryo transfer

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

AIM: To investigate reasons for the declining prevalence of cerebral palsy (CP) in children born at term in Denmark by evaluating obstetric and neonatal factors associated with CP, and their changes over time.

METHOD: In this cohort study, we included 987 495 children (504 600 [51.1%] males and 482 895 [48.9%] females) born after 37 completed gestational weeks during birth years 1997 to 2013. Risk ratios of CP for each factor were calculated with log-binominal regression analyses. Significant factors were evaluated concerning their development in prevalence over time.

RESULTS: In the antenatal period, there were significant associations with an increased risk of CP and high maternal body mass index (BMI), smoking during pregnancy, nulliparity, male sex, gestational age, and low birthweight. In the study period, fewer females smoked during pregnancy and fewer children were born post-term, dropping from 22.6% to 11.4% and 9.4% to 2.5% respectively. Conversely, the proportion of females with high BMI increased. Most significant risk factors were found in the neonatal period, with an increase in children with diagnosed birth defects and children admitted to neonatal care.

INTERPRETATION: Reasons for the declining prevalence of CP appear to be multifactorial and likely include the decline in maternal smoking and children born post-term along with centralization and advances in neonatal treatment.

OriginalsprogEngelsk
Artikelnummer15136
TidsskriftDevelopmental Medicine and Child Neurology
Sider (fra-til)1-8
Antal sider8
ISSN0012-1622
DOI
StatusE-pub ahead of print - 20 dec. 2021

Bibliografisk note

© 2021 Mac Keith Press.

ID: 70141379