Data fusion in metabolomic cancer diagnostics

Rasmus Kruse Bro; Hans Jørgen Nielsen; Francesco Savorani; Karin Kjeldahl; Ib Jarle Christensen; Nils Aage Brünner; Anders Juul Lawaetz

doi:10.1007/s11306-012-0446-0

Data fusion in metabolomic cancer diagnostics

Rasmus Kruse Bro, Hans Jørgen Nielsen, Francesco Savorani, Karin Kjeldahl, Ib Jarle Christensen, Nils Aage Brünner, Anders Juul Lawaetz

42 Citationer (Scopus)

Abstrakt

We have recently shown that fluorescence spectroscopy of plasma samples has promising abilities regarding early detection of colorectal cancer. In the present paper, these results were further developed by combining fluorescence with the biomarkers, CEA and TIMP-1 and traditional metabolomic measurements in the form of (1)H NMR spectroscopy. The results indicate that using an extensive profile established by combining such measurements together with the biomarkers is better than using single markers.

Originalsprog	Engelsk
Tidsskrift	Metabolomics
Vol/bind	9
Udgave nummer	1
Sider (fra-til)	3-8
Antal sider	6
ISSN	1573-3882
DOI	https://doi.org/10.1007/s11306-012-0446-0
Status	Udgivet - 2013

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10.1007/s11306-012-0446-0

Citationsformater

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title = "Data fusion in metabolomic cancer diagnostics",

abstract = "We have recently shown that fluorescence spectroscopy of plasma samples has promising abilities regarding early detection of colorectal cancer. In the present paper, these results were further developed by combining fluorescence with the biomarkers, CEA and TIMP-1 and traditional metabolomic measurements in the form of (1)H NMR spectroscopy. The results indicate that using an extensive profile established by combining such measurements together with the biomarkers is better than using single markers.",

author = "Bro, {Rasmus Kruse} and Nielsen, {Hans J{\o}rgen} and Francesco Savorani and Karin Kjeldahl and Christensen, {Ib Jarle} and Br{\"u}nner, {Nils Aage} and Lawaetz, {Anders Juul}",

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TY - JOUR

T1 - Data fusion in metabolomic cancer diagnostics

AU - Bro, Rasmus Kruse

AU - Nielsen, Hans Jørgen

AU - Savorani, Francesco

AU - Kjeldahl, Karin

AU - Christensen, Ib Jarle

AU - Brünner, Nils Aage

AU - Lawaetz, Anders Juul

PY - 2013

Y1 - 2013

N2 - We have recently shown that fluorescence spectroscopy of plasma samples has promising abilities regarding early detection of colorectal cancer. In the present paper, these results were further developed by combining fluorescence with the biomarkers, CEA and TIMP-1 and traditional metabolomic measurements in the form of (1)H NMR spectroscopy. The results indicate that using an extensive profile established by combining such measurements together with the biomarkers is better than using single markers.

AB - We have recently shown that fluorescence spectroscopy of plasma samples has promising abilities regarding early detection of colorectal cancer. In the present paper, these results were further developed by combining fluorescence with the biomarkers, CEA and TIMP-1 and traditional metabolomic measurements in the form of (1)H NMR spectroscopy. The results indicate that using an extensive profile established by combining such measurements together with the biomarkers is better than using single markers.

U2 - 10.1007/s11306-012-0446-0

DO - 10.1007/s11306-012-0446-0

M3 - Journal article

C2 - 23335866

VL - 9

SP - 3

EP - 8

JO - Metabolomics

JF - Metabolomics

SN - 1573-3882

IS - 1

ER -

Data fusion in metabolomic cancer diagnostics

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