Cytokine-Induced Impairment of Mitochondrial Respiration is Partly Dependent on Nitric Oxide Production

Keyphrases

• Nitric Oxide 100%
• Mitochondrial Respiration 100%
• Nitric Oxide Production 100%
• Human Islets 75%
• INS-1E Cells 62%
• Type I Diabetes 50%
• Type 1 Diabetes Mellitus (T1DM) 50%
• Respiration 50%
• Mitochondrial Dysfunction 37%
• β-cell Dysfunction 37%
• L-NMMA 25%
• ATP Production 25%
• Coupling Efficiency 25%
• Non-associated 12%
• Inflammatory Cytokines 12%
• Gene Expression 12%
• Quantitative PCR 12%
• Apoptosis 12%
• Interleukin-1β 12%
• Metabolic 12%
• Oxygen Consumption 12%
• Inducible Nitric Oxide Synthase 12%
• Cell Death 12%
• Rodent Models 12%
• Islet 12%
• Metabolic Enzymes 12%
• Methyl 12%
• Impaired Fasting Glucose 12%
• Pathogenic Role 12%
• Arginine 12%
• Changes in Gene Expression 12%
• Late Events 12%
• Nitric Oxide Synthase Inhibitors 12%
• Relevant Genes 12%
• Cytokine Signaling 12%
• Mitochondrial Oxygen Consumption 12%
• Human Pancreatic Islets 12%
• INS-1E 12%
• Event-triggered 12%
• Mitochondrial Bioenergetics 12%
• Ventilatory Response 12%
• Cytokine Therapy 12%
• Acetate Salts 12%
• Seahorse XFe24 12%

Biochemistry, Genetics and Molecular Biology

• Mitochondrial Respiration 100%
• Cytokine 100%
• Nitric Oxide 100%
• Gene Expression 11%
• Nitric Oxide Synthase 11%
• Cell Death 11%
• Adenosine Triphosphate 11%
• Oxygen Consumption 11%
• Enzyme 5%
• Proinflammatory Cytokine 5%
• Mediator 5%
• Real-Time Polymerase Chain Reaction 5%
• Signal Transduction 5%
• Arginine 5%
• Interleukin-1 5%
• Cell Destruction 5%
• Bioenergy 5%
• Seahorse 5%

Immunology and Microbiology

• Cytokine 100%
• Mitochondrial Respiration 100%
• Gene Expression 12%
• Oxygen Consumption 12%
• Cell Death 12%
• Real Time Polymerase Chain Reaction 6%
• Mediator 6%
• Interleukin-1 6%
• Proinflammatory Cytokine 6%
• Signal Transduction 6%
• Cytokine Signaling 6%
• Bioenergy 6%
• Cell Destruction 6%
• Seahorse 6%