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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Cryopreservation of ovarian tissue for fertility preservation in young female oncological patients

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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Vis graf over relationer
Girls and women suffering from a cancer that requires treatment with gonadotoxic drugs may experience cessation of reproductive function as a side effect due to obliteration of the ovarian pool of follicles. Techniques are now available for fertility preservation, such as cryopreservation of mature oocytes, embryos or ovarian cortical tissue. Whereas collection of mature oocytes and embryos requires at least a 2-week period, ovarian tissue may on short notice be frozen prior to treatment and can be transplanted back into women with ovarian failure. Transplanted frozen/thawed tissue supports survival and growth of follicles, giving rise to menstrual cycles and hormone production for several years. Worldwide, the procedure has resulted in the birth of 15 healthy children. Many cancer patients including girls and young women want fertility preservation, and the techniques are now being further developed and implemented in several centers.
OriginalsprogEngelsk
TidsskriftFuture oncology (London, England)
Vol/bind8
Udgave nummer5
Sider (fra-til)595-608
Antal sider14
DOI
StatusUdgivet - 2012

ID: 36330571