TY - JOUR
T1 - Cross-reactions between Haemophilus influenzae and nineteen other bacterial species
AU - Schiøtz, P O
AU - Høiby, N
AU - Hertz, J B
PY - 1979/12
Y1 - 1979/12
N2 - Forty-one different antigens were demonstrated in an antigen preparation obtained by sonication of a Haemophilus influenzae (H. influenzae) type b strain, using crossed immunoelectrophoresis and antiserum obtained from rabbits. Antigens were characterized by absorption experiments with whole heat-killed bacteria, temperature resistance and protein and polysaccharide staining. Cross-reactions between H. influenzae type b and 19 other bacterial species were studied by various quantitative immunoelectrophoretic methods, using the reference system. A non-capsulated H. influenzae cross-reacted extensively (41 antigens) with H. influenzae type b and Haemophilus parainfluenzae, and Haemophilus haemolyticus showed considerable cross-reactivity with H. influenzae type b (26 and 32 antigens respectively), while antigens from eight other bacterial species cross-reacted to varying degrees with one to five H. influenzae antigens.
AB - Forty-one different antigens were demonstrated in an antigen preparation obtained by sonication of a Haemophilus influenzae (H. influenzae) type b strain, using crossed immunoelectrophoresis and antiserum obtained from rabbits. Antigens were characterized by absorption experiments with whole heat-killed bacteria, temperature resistance and protein and polysaccharide staining. Cross-reactions between H. influenzae type b and 19 other bacterial species were studied by various quantitative immunoelectrophoretic methods, using the reference system. A non-capsulated H. influenzae cross-reacted extensively (41 antigens) with H. influenzae type b and Haemophilus parainfluenzae, and Haemophilus haemolyticus showed considerable cross-reactivity with H. influenzae type b (26 and 32 antigens respectively), while antigens from eight other bacterial species cross-reacted to varying degrees with one to five H. influenzae antigens.
KW - Antigens, Bacterial/analysis
KW - Bacteria/immunology
KW - Cross Reactions
KW - Epitopes
KW - Haemophilus influenzae/immunology
KW - Immunoelectrophoresis, Two-Dimensional/methods
KW - Polysaccharides, Bacterial/immunology
KW - Species Specificity
U2 - 10.1111/j.1699-0463.1979.tb02448.x
DO - 10.1111/j.1699-0463.1979.tb02448.x
M3 - Journal article
C2 - 94235
SN - 0105-0656
VL - 87
SP - 337
EP - 344
JO - Acta pathologica et microbiologica Scandinavica. Section B, Microbiology
JF - Acta pathologica et microbiologica Scandinavica. Section B, Microbiology
IS - 6
ER -