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Region Hovedstaden - en del af Københavns Universitetshospital
E-pub ahead of print

COVID-19 in adult acute myeloid leukemia patients: a long-term followup study from the European Hematology Association survey (EPICOVIDEHA)

Publikation: Bidrag til tidsskriftTidsskriftartikelpeer review

  • Francesco Marchesi
  • Jon Salmanton-García
  • Ziad Emarah
  • Klára Piukovics
  • Marcio Nucci
  • Alberto López-García
  • Zdeněk Ráčil
  • Francesca Farina
  • Marina Popova
  • Sofia Zompi
  • Ernesta Audisio
  • Marie-Pierre Ledoux
  • Luisa Verga
  • Barbora Weinbergerová
  • Tomas Szotkovski
  • Maria Gomes Da Silva
  • Nicola Fracchiolla
  • Nick De Jonge
  • Graham Collins
  • Monia Marchetti
  • Gabriele Magliano
  • Carolina García-Vidal
  • Monika M Biernat
  • Jaap Van Doesum
  • Marina Machado
  • Fatih Demirkan
  • Murtadha Al-Khabori
  • Pavel Žák
  • Benjamín Víšek
  • Igor Stoma
  • Gustavo-Adolfo Méndez
  • Johan Maertens
  • Nina Khanna
  • Ildefonso Espigado
  • Giulia Dragonetti
  • Luana Fianchi
  • Maria Ilaria Del Principe
  • Alba Cabirta
  • Irati Ormazabal-Vélez
  • Ozren Jaksic
  • Caterina Buquicchio
  • Valentina Bonuomo
  • Josip Batinić
  • Ali S Omrani
  • Sylvain Lamure
  • Olimpia Finizio
  • Noemí Fernández
  • Iker Falces-Romero
  • Ola Blennow
  • Rui Bergantim
  • Natasha Ali
  • Sein Win
  • Jens Van Praet
  • Maria Chiara Tisi
  • Ayten Shirinova
  • Martin Schönlein
  • Juergen Prattes
  • Monica Piedimonte
  • Verena Petzer
  • Milan Navrátil
  • Austin Kulasekararaj
  • Pavel Jindra
  • Jiří Sramek
  • Andreas Glenthøj
  • Rita Fazzi
  • Cristina De Ramón-Sánchez
  • Chiara Cattaneo
  • Maria Calbacho
  • Nathan C Bahr
  • Shaimaa El-Ashwah
  • Raul Cordoba
  • Michaela Hanakova
  • Giovanni Zambrotta
  • Mariarita Sciumè
  • Stephen Booth
  • Raquel Nunes Rodrigues
  • Maria Vittoria Sacchi
  • Nicole García-Poutón
  • Juan-Alberto Martín-González
  • Sofya Khostelidi
  • Stefanie Gräfe
  • Laman Rahimli
  • Emanuele Ammatuna
  • Alessandro Busca
  • Paolo Corradini
  • Martin Hoenigl
  • Nikolai Klimko
  • Philipp Koehler
  • Antonio Pagliuca
  • Francesco Passamonti
  • Oliver A Cornely
  • Livio Pagano
Vis graf over relationer

Patients with acute myeloid leukemia (AML) are at high risk of mortality from coronavirus disease 2019 (COVID-19). The optimal management of AML patients with COVID-19 has not been established. Our multicenter study included 388 adult AML patients with COVID-19 diagnosis between February 2020 and October 2021. The vast majority were receiving or had received AML treatment in the prior 3 months. COVID-19 was severe in 41.2% and critical in 21.1% of cases. The chemotherapeutic schedule was modified in 174 patients (44.8%), delayed in 68 and permanently discontinued in 106. After a median follow-up of 325 days, 180 patients (46.4%) had died; death was attributed to COVID-19 (43.3%), AML (26.1%) or to a combination of both (26.7%), whereas in 3.9% of cases the reason was unknown. Active disease, older age, and treatment discontinuation were associated with death, whereas AML treatment delay was protective. Seventy-nine patients had a simultaneous AML and COVID-19 diagnosis, with an improved survival when AML treatment could be delayed (80%; p.

OriginalsprogEngelsk
TidsskriftHaematologica
ISSN0390-6078
DOI
StatusE-pub ahead of print - 12 maj 2022

ID: 78228034