Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay - Forskning - Region Hovedstaden

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Region Hovedstaden - en del af Københavns Universitetshospital

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Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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https://doi.org/10.1186/1476-4598-12-95
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Simon Welner
Nicole Hartwig Trier
Morten Frisch
Henning Locht
Paul Robert Hansen
Gunnar Houen

Parker Instituttet , Bispebjerg og Frederiksberg Hospital

Vis graf over relationer

Centromere protein-F (CENP-F) is a large nuclear protein of 367 kDa, which is involved in multiple mitosis-related events such as proper assembly of the kinetochores, stabilization of heterochromatin, chromosome alignment and mitotic checkpoint signaling. Several studies have shown a correlation between CENP-F and cancer, e.g. the expression of CENP-F has been described to be upregulated in cancer cells. Furthermore, several studies have described a significant correlation between the expression of autoantibodies to CENP-F and cancer.

Originalsprog	Engelsk
Tidsskrift	Molecular Cancer
Vol/bind	12
Udgave nummer	1
Sider (fra-til)	95
ISSN	1476-4598
DOI	https://doi.org/10.1186/1476-4598-12-95
Status	Udgivet - 2013

ID: 43197481