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Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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  • Simon Welner
  • Nicole Hartwig Trier
  • Morten Frisch
  • Henning Locht
  • Paul Robert Hansen
  • Gunnar Houen
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Centromere protein-F (CENP-F) is a large nuclear protein of 367 kDa, which is involved in multiple mitosis-related events such as proper assembly of the kinetochores, stabilization of heterochromatin, chromosome alignment and mitotic checkpoint signaling. Several studies have shown a correlation between CENP-F and cancer, e.g. the expression of CENP-F has been described to be upregulated in cancer cells. Furthermore, several studies have described a significant correlation between the expression of autoantibodies to CENP-F and cancer.
OriginalsprogEngelsk
TidsskriftMolecular Cancer
Vol/bind12
Udgave nummer1
Sider (fra-til)95
ISSN1476-4598
DOI
StatusUdgivet - 2013

ID: 43197481