@article{3c373bb54d3a4cdba0c16ca193167bd7,
title = "Correlates for disease progression and prognosis during concurrent HIV/TB infection",
abstract = "Mycobacterium tuberculosis (Mtb) and the human immunodeficiency virus (HIV) are both life-threatening pathogens in their own right, but their synergic effects on the immune system during co-infection markedly enhance their effect on the host. This review focuses on the bidirectional interaction between HIV and Mtb and discusses the relevance of sputum smear examination, CD4+ counts, viral load at baseline and after initiation of anti-retroviral therapy, as well as additional existing and new potential immune correlates of disease progression and prognosis. These markers include beta2-microglobulin, neopterin, tumor necrosis factor receptor II (TNFRII), CD8+/CD38+, soluble urokinase plasminogen activator receptor (suPAR) and CXCL10 (or IP-10).",
keywords = "Cytokines, Dendritic Cells, Disease Progression, HIV, HIV Infections, Humans, Mycobacterium tuberculosis, Prognosis, Tuberculosis",
author = "{Djoba Siawaya}, {Joel Fleury} and Morten Ruhwald and Jesper Eugen-Olsen and Gerhard Walzl",
year = "2007",
doi = "10.1016/j.ijid.2007.02.001",
language = "English",
volume = "11",
pages = "289--99",
journal = "International Journal of Infectious Diseases",
issn = "1201-9712",
publisher = "Elsevier Ltd",
number = "4",
}