Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort

C Ryberg; E Rostrup; O B Paulson; F Barkhof; P Scheltens; E C W van Straaten; W M van der Flier; F Fazekas; R Schmidt; J M Ferro; H Baezner; T Erkinjuntti; H Jokinen; L-O Wahlund; A Poggesi; L Pantoni; D Inzitari; G Waldemar; LADIS study group; Bjørn Ebdrup

doi:10.1016/j.jns.2011.05.002

Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort

C Ryberg, E Rostrup, O B Paulson, F Barkhof, P Scheltens, E C W van Straaten, W M van der Flier, F Fazekas, R Schmidt, J M Ferro, H Baezner, T Erkinjuntti, H Jokinen, L-O Wahlund, A Poggesi, L Pantoni, D Inzitari, G Waldemar, LADIS study group, Bjørn Ebdrup

65 Citationer (Scopus)

Abstract

The aim of this 3-year follow-up study was to investigate whether corpus callosum (CC) atrophy may predict future motor and cognitive impairment in an elderly population. On baseline MRI from 563 subjects with age-related white matter changes (ARWMC) from the Leukoaraiosis And DISability (LADIS) study, the CC was segmented and subdivided into five anterior-posterior regions (CC1-CC5). Associations between the CC areas and decline in motor performance and cognitive functions over a 3-year period were analyzed. CC atrophy at baseline was significantly associated with impaired cognitive performance (p

Originalsprog	Engelsk
Tidsskrift	Journal of the Neurological Sciences
Vol/bind	307
Udgave nummer	1-2
Sider (fra-til)	100-5
Antal sider	6
ISSN	0022-510X
DOI	https://doi.org/10.1016/j.jns.2011.05.002
Status	Udgivet - 2011

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10.1016/j.jns.2011.05.002

Citationsformater

Ryberg, C., Rostrup, E., Paulson, O. B., Barkhof, F., Scheltens, P., van Straaten, E. C. W., van der Flier, W. M., Fazekas, F., Schmidt, R., Ferro, J. M., Baezner, H., Erkinjuntti, T., Jokinen, H., Wahlund, L.-O., Poggesi, A., Pantoni, L., Inzitari, D., Waldemar, G., LADIS study group, & Ebdrup, B. (2011). Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort. Journal of the Neurological Sciences, 307(1-2), 100-5. https://doi.org/10.1016/j.jns.2011.05.002

Ryberg, C, Rostrup, E , Paulson, OB, Barkhof, F, Scheltens, P, van Straaten, ECW, van der Flier, WM, Fazekas, F, Schmidt, R, Ferro, JM, Baezner, H, Erkinjuntti, T, Jokinen, H, Wahlund, L-O, Poggesi, A, Pantoni, L, Inzitari, D, Waldemar, G, LADIS study group & Ebdrup, B 2011, 'Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort', Journal of the Neurological Sciences, bind 307, nr. 1-2, s. 100-5. https://doi.org/10.1016/j.jns.2011.05.002

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title = "Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort",

abstract = "The aim of this 3-year follow-up study was to investigate whether corpus callosum (CC) atrophy may predict future motor and cognitive impairment in an elderly population. On baseline MRI from 563 subjects with age-related white matter changes (ARWMC) from the Leukoaraiosis And DISability (LADIS) study, the CC was segmented and subdivided into five anterior-posterior regions (CC1-CC5). Associations between the CC areas and decline in motor performance and cognitive functions over a 3-year period were analyzed. CC atrophy at baseline was significantly associated with impaired cognitive performance (p",

author = "C Ryberg and E Rostrup and Paulson, {O B} and F Barkhof and P Scheltens and {van Straaten}, {E C W} and {van der Flier}, {W M} and F Fazekas and R Schmidt and Ferro, {J M} and H Baezner and T Erkinjuntti and H Jokinen and L-O Wahlund and A Poggesi and L Pantoni and D Inzitari and G Waldemar and {LADIS study group} and Bj{\o}rn Ebdrup",

year = "2011",

doi = "10.1016/j.jns.2011.05.002",

language = "English",

volume = "307",

pages = "100--5",

journal = "Journal of the Neurological Sciences",

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TY - JOUR

T1 - Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort

AU - Ryberg, C

AU - Rostrup, E

AU - Paulson, O B

AU - Barkhof, F

AU - Scheltens, P

AU - van Straaten, E C W

AU - van der Flier, W M

AU - Fazekas, F

AU - Schmidt, R

AU - Ferro, J M

AU - Baezner, H

AU - Erkinjuntti, T

AU - Jokinen, H

AU - Wahlund, L-O

AU - Poggesi, A

AU - Pantoni, L

AU - Inzitari, D

AU - Waldemar, G

AU - LADIS study group

AU - Ebdrup, Bjørn

PY - 2011

Y1 - 2011

N2 - The aim of this 3-year follow-up study was to investigate whether corpus callosum (CC) atrophy may predict future motor and cognitive impairment in an elderly population. On baseline MRI from 563 subjects with age-related white matter changes (ARWMC) from the Leukoaraiosis And DISability (LADIS) study, the CC was segmented and subdivided into five anterior-posterior regions (CC1-CC5). Associations between the CC areas and decline in motor performance and cognitive functions over a 3-year period were analyzed. CC atrophy at baseline was significantly associated with impaired cognitive performance (p

AB - The aim of this 3-year follow-up study was to investigate whether corpus callosum (CC) atrophy may predict future motor and cognitive impairment in an elderly population. On baseline MRI from 563 subjects with age-related white matter changes (ARWMC) from the Leukoaraiosis And DISability (LADIS) study, the CC was segmented and subdivided into five anterior-posterior regions (CC1-CC5). Associations between the CC areas and decline in motor performance and cognitive functions over a 3-year period were analyzed. CC atrophy at baseline was significantly associated with impaired cognitive performance (p

U2 - 10.1016/j.jns.2011.05.002

DO - 10.1016/j.jns.2011.05.002

M3 - Journal article

C2 - 21621224

SN - 0022-510X

VL - 307

SP - 100

EP - 105

JO - Journal of the Neurological Sciences

JF - Journal of the Neurological Sciences

IS - 1-2

ER -

Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort

Abstract

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