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Udgivet

Continuous thoracic extradural 0.5% bupivacaine with or without morphine: effect on quality of blockade, lung function and the surgical stress response.

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  • N B Scott
  • T Mogensen
  • D Bigler
  • C Lund
  • H Kehlet
Vis graf over relationer
Twenty-two patients undergoing upper abdominal surgery were entered into a randomized, double-blind study to receive extradural (T7-T8) 0.5% bupivacaine 9 ml followed by 25 mg h-1 with or without additional extradural morphine (bolus 4 mg plus 0.5 mg h-1), for 16 h after operation. Addition of morphine was associated with total alleviation of pain, and a stable level of sensory analgesia, but not with changes in blood glucose and cortisol concentrations or postoperative impairment of lung function (PEFR, FEV1, FVC). Two patients were withdrawn because of hypotension or respiratory depression.
Bidragets oversatte titelContinuous thoracic extradural 0.5% bupivacaine with or without morphine: effect on quality of blockade, lung function and the surgical stress response.
OriginalsprogEngelsk
TidsskriftBritish Journal of Anaesthesia
Vol/bind62
Udgave nummer3
Sider (fra-til)253-257
Antal sider5
ISSN0007-0912
StatusUdgivet - 1989

ID: 32517571