Considerable haplotype diversity within the 23kb encompassing the ADH7 gene

Yi Han, Hiroki Oota, Michael V Osier, Andrew J Pakstis, William C Speed, Adekunle Odunsi, Friday Okonofua, Sylvester L B Kajuna, Nganyirwa J Karoma, Selemani Kungulilo, Elena Grigorenko, Olga V Zhukova, Batsheva Bonne-Tamir, Ru-B Lu, Josef Parnas, Leslie O Schulz, Judith R Kidd, Kenneth K Kidd

    19 Citationer (Scopus)

    Abstract

    Of the seven known human alcohol dehydrogenase (ADH) genes, the non-liver expressed ADH7 gene codes for the enzyme with the highest maximal activity for ethanol. Previous study from our laboratory has suggested that ADH7 has an epistatic role for protection against alcoholism based on a single ADH7 SNP.
    OriginalsprogEngelsk
    TidsskriftAlcoholism: Clinical and Experimental Research
    Vol/bind29
    Udgave nummer12
    Sider (fra-til)2091-100
    Antal sider10
    ISSN0145-6008
    StatusUdgivet - 2005

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