Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Configural memory of a blending aromatic mixture reflected in activation of the left orbital part of the inferior frontal gyrus

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Harvard

Sinding, C, Hummel, T, Béno, N, Prescott, J, Bensafi, M, Coureaud, G & Thomas-Danguin, T 2021, 'Configural memory of a blending aromatic mixture reflected in activation of the left orbital part of the inferior frontal gyrus', Behavioural Brain Research, bind 402, 113088, s. 113088. https://doi.org/10.1016/j.bbr.2020.113088

APA

Sinding, C., Hummel, T., Béno, N., Prescott, J., Bensafi, M., Coureaud, G., & Thomas-Danguin, T. (2021). Configural memory of a blending aromatic mixture reflected in activation of the left orbital part of the inferior frontal gyrus. Behavioural Brain Research, 402, 113088. [113088]. https://doi.org/10.1016/j.bbr.2020.113088

CBE

MLA

Vancouver

Author

Sinding, C ; Hummel, T ; Béno, N ; Prescott, J ; Bensafi, M ; Coureaud, G ; Thomas-Danguin, T. / Configural memory of a blending aromatic mixture reflected in activation of the left orbital part of the inferior frontal gyrus. I: Behavioural Brain Research. 2021 ; Bind 402. s. 113088.

Bibtex

@article{3975f31613d946d688a0f1be430e8d59,
title = "Configural memory of a blending aromatic mixture reflected in activation of the left orbital part of the inferior frontal gyrus",
abstract = "Blending aromatic mixtures components naturally fuse to form a unique odor - a configuration- qualitatively different from each component's odor. Repeated exposure to the components either in the mixture or separately, favors respectively, configural and elemental processings. The neural bases of such processes are still unknown. We examined the brain correlates of the experienced-induced configural processing of a well-known model of binary blending odor mixture, the aromatic pineapple blending (AB, ethyl maltol + ethyl isobutyrate). Before fMRI recording, half of the participants were repeatedly exposed to the mixture (AB, group Gmix), with the other half exposed to its separate components (A and B; Gcomp). During the fMRI recording, all participants were stimulated with the mixture (AB) and the components (A and B). Finally, participants rated the number of odors perceived for each stimulus. Gmix perceived the AB mixture as less complex than did Gcomp. While Gcomp perceived the mixture as more complex than its components, Gmix did not. These results show the presence of experience-induced configural or elemental processing of the AB mixture in each group. Contrasting the brain activity of Gcomp and Gmix, when stimulated with AB, revealed higher activation in the left orbital part of the inferior frontal gyrus. This result sheds light on this area's function, commonly found activated in olfactory studies, and closely connected with the lateral orbitofrontal cortex. We discuss the role of this area as a mediator of configural percepts between temporal and orbitofrontal areas involved in configural memory processes.",
keywords = "Blending mixture, Experience, fMRI, Learning, Odor, Olfaction",
author = "C Sinding and T Hummel and N B{\'e}no and J Prescott and M Bensafi and G Coureaud and T Thomas-Danguin",
note = "Copyright {\textcopyright} 2020. Published by Elsevier B.V.",
year = "2021",
month = mar,
day = "26",
doi = "10.1016/j.bbr.2020.113088",
language = "English",
volume = "402",
pages = "113088",
journal = "Behavioural Brain Research",
issn = "0166-4328",
publisher = "Elsevier BV",

}

RIS

TY - JOUR

T1 - Configural memory of a blending aromatic mixture reflected in activation of the left orbital part of the inferior frontal gyrus

AU - Sinding, C

AU - Hummel, T

AU - Béno, N

AU - Prescott, J

AU - Bensafi, M

AU - Coureaud, G

AU - Thomas-Danguin, T

N1 - Copyright © 2020. Published by Elsevier B.V.

PY - 2021/3/26

Y1 - 2021/3/26

N2 - Blending aromatic mixtures components naturally fuse to form a unique odor - a configuration- qualitatively different from each component's odor. Repeated exposure to the components either in the mixture or separately, favors respectively, configural and elemental processings. The neural bases of such processes are still unknown. We examined the brain correlates of the experienced-induced configural processing of a well-known model of binary blending odor mixture, the aromatic pineapple blending (AB, ethyl maltol + ethyl isobutyrate). Before fMRI recording, half of the participants were repeatedly exposed to the mixture (AB, group Gmix), with the other half exposed to its separate components (A and B; Gcomp). During the fMRI recording, all participants were stimulated with the mixture (AB) and the components (A and B). Finally, participants rated the number of odors perceived for each stimulus. Gmix perceived the AB mixture as less complex than did Gcomp. While Gcomp perceived the mixture as more complex than its components, Gmix did not. These results show the presence of experience-induced configural or elemental processing of the AB mixture in each group. Contrasting the brain activity of Gcomp and Gmix, when stimulated with AB, revealed higher activation in the left orbital part of the inferior frontal gyrus. This result sheds light on this area's function, commonly found activated in olfactory studies, and closely connected with the lateral orbitofrontal cortex. We discuss the role of this area as a mediator of configural percepts between temporal and orbitofrontal areas involved in configural memory processes.

AB - Blending aromatic mixtures components naturally fuse to form a unique odor - a configuration- qualitatively different from each component's odor. Repeated exposure to the components either in the mixture or separately, favors respectively, configural and elemental processings. The neural bases of such processes are still unknown. We examined the brain correlates of the experienced-induced configural processing of a well-known model of binary blending odor mixture, the aromatic pineapple blending (AB, ethyl maltol + ethyl isobutyrate). Before fMRI recording, half of the participants were repeatedly exposed to the mixture (AB, group Gmix), with the other half exposed to its separate components (A and B; Gcomp). During the fMRI recording, all participants were stimulated with the mixture (AB) and the components (A and B). Finally, participants rated the number of odors perceived for each stimulus. Gmix perceived the AB mixture as less complex than did Gcomp. While Gcomp perceived the mixture as more complex than its components, Gmix did not. These results show the presence of experience-induced configural or elemental processing of the AB mixture in each group. Contrasting the brain activity of Gcomp and Gmix, when stimulated with AB, revealed higher activation in the left orbital part of the inferior frontal gyrus. This result sheds light on this area's function, commonly found activated in olfactory studies, and closely connected with the lateral orbitofrontal cortex. We discuss the role of this area as a mediator of configural percepts between temporal and orbitofrontal areas involved in configural memory processes.

KW - Blending mixture

KW - Experience

KW - fMRI

KW - Learning

KW - Odor

KW - Olfaction

UR - http://www.scopus.com/inward/record.url?scp=85098858356&partnerID=8YFLogxK

U2 - 10.1016/j.bbr.2020.113088

DO - 10.1016/j.bbr.2020.113088

M3 - Journal article

C2 - 33358920

VL - 402

SP - 113088

JO - Behavioural Brain Research

JF - Behavioural Brain Research

SN - 0166-4328

M1 - 113088

ER -

ID: 61663078