Concentration-dependent neurotoxicity of articaine: an electrophysiological and stereological study of the rat sciatic nerve

Søren Hillerup; Merete Bakke; Jytte Overgaard Larsen; Carsten Eckhart Thomsen; Thomas Alexander Gerds

doi:10.1213/ANE.0b013e3182172a2e

Concentration-dependent neurotoxicity of articaine: an electrophysiological and stereological study of the rat sciatic nerve

Søren Hillerup, Merete Bakke, Jytte Overgaard Larsen, Carsten Eckhart Thomsen, Thomas Alexander Gerds

Afdeling for Kæbekirurgi HOC

28 Citationer (Scopus)

Abstract

We performed this study to quantify the detrimental effect of intraneural injection of 50 μL of saline, articaine 2%, or articaine 4% in the rat sciatic nerve.

Originalsprog	Engelsk
Tidsskrift	Anesthesia and Analgesia
Vol/bind	112
Udgave nummer	6
Sider (fra-til)	1330-8
Antal sider	9
ISSN	0003-2999
DOI	https://doi.org/10.1213/ANE.0b013e3182172a2e
Status	Udgivet - 1 jun. 2011

Adgang til dokumentet

10.1213/ANE.0b013e3182172a2e

Andre filer og links

Link to publication in Scopus

Citationsformater

@article{369b598b1f774a4ebf257435bd7d6e67,

title = "Concentration-dependent neurotoxicity of articaine: an electrophysiological and stereological study of the rat sciatic nerve",

abstract = "We performed this study to quantify the detrimental effect of intraneural injection of 50 μL of saline, articaine 2\%, or articaine 4\% in the rat sciatic nerve.",

keywords = "Animals, Axons, Carticaine, Dose-Response Relationship, Drug, Electrophysiology, Female, Lumbar Vertebrae, Models, Statistical, Myelin Sheath, Neural Conduction, Rats, Rats, Wistar, Sciatic Nerve, Time Factors",

author = "S{\o}ren Hillerup and Merete Bakke and Larsen, \{Jytte Overgaard\} and Thomsen, \{Carsten Eckhart\} and Gerds, \{Thomas Alexander\}",

year = "2011",

month = jun,

day = "1",

doi = "10.1213/ANE.0b013e3182172a2e",

language = "English",

volume = "112",

pages = "1330--8",

journal = "Anesthesia and Analgesia",

issn = "0003-2999",

publisher = "Lippincott Williams and Wilkins",

number = "6",

}

TY - JOUR

T1 - Concentration-dependent neurotoxicity of articaine: an electrophysiological and stereological study of the rat sciatic nerve

AU - Hillerup, Søren

AU - Bakke, Merete

AU - Larsen, Jytte Overgaard

AU - Thomsen, Carsten Eckhart

AU - Gerds, Thomas Alexander

PY - 2011/6/1

Y1 - 2011/6/1

N2 - We performed this study to quantify the detrimental effect of intraneural injection of 50 μL of saline, articaine 2%, or articaine 4% in the rat sciatic nerve.

AB - We performed this study to quantify the detrimental effect of intraneural injection of 50 μL of saline, articaine 2%, or articaine 4% in the rat sciatic nerve.

KW - Animals

KW - Axons

KW - Carticaine

KW - Dose-Response Relationship, Drug

KW - Electrophysiology

KW - Female

KW - Lumbar Vertebrae

KW - Models, Statistical

KW - Myelin Sheath

KW - Neural Conduction

KW - Rats

KW - Rats, Wistar

KW - Sciatic Nerve

KW - Time Factors

UR - https://www.scopus.com/pages/publications/79958100805

U2 - 10.1213/ANE.0b013e3182172a2e

DO - 10.1213/ANE.0b013e3182172a2e

M3 - Journal article

C2 - 21467556

SN - 0003-2999

VL - 112

SP - 1330

EP - 1338

JO - Anesthesia and Analgesia

JF - Anesthesia and Analgesia

IS - 6

ER -

Concentration-dependent neurotoxicity of articaine: an electrophysiological and stereological study of the rat sciatic nerve

Abstract

Adgang til dokumentet

Andre filer og links

Fingeraftryk

Citationsformater