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Computer tomography guided lung biopsy using interactive breath-hold control: a randomized study

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@article{893b64fa0b9e43818889ff56160ebb74,
title = "Computer tomography guided lung biopsy using interactive breath-hold control: a randomized study",
abstract = "BACKGROUND: Interactive breath-hold control (IBC) may improve the accuracy and decrease the complication rate of computed tomography (CT)-guided lung biopsy, but this presumption has not been proven in a randomized study.METHODS: Patients admitted for CT-guided lung biopsy were randomized to biopsy either with (N=201) or without (N=206) IBC. Biopsy accuracy, procedure time, radiation, and complications were compared in the two groups. Predictors for pneumothorax were analyzed.RESULTS: Procedures performed with the use of IBC (N=130) did not show higher biopsy accuracy (P=0.979) but were associated with a higher risk of pneumothorax (P=0.022) compared to procedures without the use of IBC (N=171). Overall, 50{\%} of the biopsies were malignant, 13{\%} were benign, and 33{\%} were inconclusive (4{\%} missing). Long needle time (P=0.037) and small nodule size (P=0.001) were predictors of pneumothorax.CONCLUSIONS: The use of IBC for CT-guided lung biopsy was not an advantage for unselected patients in our care, since it did not improve the biopsy accuracy and the risk of pneumothorax was increased.",
keywords = "Journal Article",
author = "Haseem Ashraf and Shella Krag-Andersen and Matiullah Naqibullah and Valentina Minddal and Annette N{\o}rgaard and Naur, {Therese Maria Henriette} and Myschetzky, {Peter Sand} and Clementsen, {Paul Frost}",
year = "2017",
month = "6",
doi = "10.21037/atm.2017.05.10",
language = "English",
volume = "5",
pages = "253",
journal = "Annals of Translational Medicine",
issn = "1479-5876",
publisher = "BioMed Central Ltd",
number = "12",

}

RIS

TY - JOUR

T1 - Computer tomography guided lung biopsy using interactive breath-hold control

T2 - a randomized study

AU - Ashraf, Haseem

AU - Krag-Andersen, Shella

AU - Naqibullah, Matiullah

AU - Minddal, Valentina

AU - Nørgaard, Annette

AU - Naur, Therese Maria Henriette

AU - Myschetzky, Peter Sand

AU - Clementsen, Paul Frost

PY - 2017/6

Y1 - 2017/6

N2 - BACKGROUND: Interactive breath-hold control (IBC) may improve the accuracy and decrease the complication rate of computed tomography (CT)-guided lung biopsy, but this presumption has not been proven in a randomized study.METHODS: Patients admitted for CT-guided lung biopsy were randomized to biopsy either with (N=201) or without (N=206) IBC. Biopsy accuracy, procedure time, radiation, and complications were compared in the two groups. Predictors for pneumothorax were analyzed.RESULTS: Procedures performed with the use of IBC (N=130) did not show higher biopsy accuracy (P=0.979) but were associated with a higher risk of pneumothorax (P=0.022) compared to procedures without the use of IBC (N=171). Overall, 50% of the biopsies were malignant, 13% were benign, and 33% were inconclusive (4% missing). Long needle time (P=0.037) and small nodule size (P=0.001) were predictors of pneumothorax.CONCLUSIONS: The use of IBC for CT-guided lung biopsy was not an advantage for unselected patients in our care, since it did not improve the biopsy accuracy and the risk of pneumothorax was increased.

AB - BACKGROUND: Interactive breath-hold control (IBC) may improve the accuracy and decrease the complication rate of computed tomography (CT)-guided lung biopsy, but this presumption has not been proven in a randomized study.METHODS: Patients admitted for CT-guided lung biopsy were randomized to biopsy either with (N=201) or without (N=206) IBC. Biopsy accuracy, procedure time, radiation, and complications were compared in the two groups. Predictors for pneumothorax were analyzed.RESULTS: Procedures performed with the use of IBC (N=130) did not show higher biopsy accuracy (P=0.979) but were associated with a higher risk of pneumothorax (P=0.022) compared to procedures without the use of IBC (N=171). Overall, 50% of the biopsies were malignant, 13% were benign, and 33% were inconclusive (4% missing). Long needle time (P=0.037) and small nodule size (P=0.001) were predictors of pneumothorax.CONCLUSIONS: The use of IBC for CT-guided lung biopsy was not an advantage for unselected patients in our care, since it did not improve the biopsy accuracy and the risk of pneumothorax was increased.

KW - Journal Article

U2 - 10.21037/atm.2017.05.10

DO - 10.21037/atm.2017.05.10

M3 - Journal article

VL - 5

SP - 253

JO - Annals of Translational Medicine

JF - Annals of Translational Medicine

SN - 1479-5876

IS - 12

ER -

ID: 51564668