Complete tyrosine O-sulfation of gastrin in adult and neonatal cat pancreas

P Cantor; B N Andersen; J F Rehfeld

doi:10.1016/0014-5793(86)80175-2

Complete tyrosine O-sulfation of gastrin in adult and neonatal cat pancreas

P Cantor, B N Andersen, J F Rehfeld

14 Citationer (Scopus)

Abstract

We have found gastrin in both the adult and neonatal cat pancreas. In contrast with the main production sites, antrum and duodenum, gastrin in the pancreas occurs in a single molecular form, tyrosine O-sulfated gastrin-17. Since tyrosine sulfation increases the pancreozymic effect of gastrin, the complete sulfation seems functionally expedient.

Originalsprog	Engelsk
Tidsskrift	FEBS Letters
Vol/bind	195
Udgave nummer	1-2
Sider (fra-til)	272-4
Antal sider	3
ISSN	0014-5793
DOI	https://doi.org/10.1016/0014-5793(86)80175-2
Status	Udgivet - 20 jan. 1986
Udgivet eksternt	Ja

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abstract = "We have found gastrin in both the adult and neonatal cat pancreas. In contrast with the main production sites, antrum and duodenum, gastrin in the pancreas occurs in a single molecular form, tyrosine O-sulfated gastrin-17. Since tyrosine sulfation increases the pancreozymic effect of gastrin, the complete sulfation seems functionally expedient.",

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year = "1986",

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T1 - Complete tyrosine O-sulfation of gastrin in adult and neonatal cat pancreas

AU - Cantor, P

AU - Andersen, B N

AU - Rehfeld, J F

PY - 1986/1/20

Y1 - 1986/1/20

N2 - We have found gastrin in both the adult and neonatal cat pancreas. In contrast with the main production sites, antrum and duodenum, gastrin in the pancreas occurs in a single molecular form, tyrosine O-sulfated gastrin-17. Since tyrosine sulfation increases the pancreozymic effect of gastrin, the complete sulfation seems functionally expedient.

AB - We have found gastrin in both the adult and neonatal cat pancreas. In contrast with the main production sites, antrum and duodenum, gastrin in the pancreas occurs in a single molecular form, tyrosine O-sulfated gastrin-17. Since tyrosine sulfation increases the pancreozymic effect of gastrin, the complete sulfation seems functionally expedient.

KW - Animals

KW - Animals, Newborn

KW - Cats

KW - Dogs

KW - Gastrins/metabolism

KW - Pancreas/metabolism

KW - Protein Processing, Post-Translational

KW - Tyrosine/analogs & derivatives

UR - https://www.scopus.com/pages/publications/0023053042

U2 - 10.1016/0014-5793(86)80175-2

DO - 10.1016/0014-5793(86)80175-2

M3 - Journal article

C2 - 3943612

SN - 0014-5793

VL - 195

SP - 272

EP - 274

JO - FEBS Letters

JF - FEBS Letters

IS - 1-2

ER -

Complete tyrosine O-sulfation of gastrin in adult and neonatal cat pancreas

Abstract

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