TY - GEN
T1 - Comparison of three nonlinear filters for fault detection in continuous glucose monitors.
AU - Mahmoudi, Zeinab
AU - Wendt, Sabrina Lyngbye
AU - Boiroux, Dimitri
AU - Hagdrup, Morten
AU - Norgaard, Kirsten
AU - Poulsen, Niels Kjolstad
AU - Madsen, Henrik
AU - Jorgensen, John Bagterp
PY - 2016
Y1 - 2016
N2 - The purpose of this study is to compare the performance of three nonlinear filters in online drift detection of continuous glucose monitors. The nonlinear filters are the extended Kalman filter (EKF), the unscented Kalman filter (UKF), and the particle filter (PF). They are all based on a nonlinear model of the glucose-insulin dynamics in people with type 1 diabetes. Drift is modelled by a Gaussian random walk and is detected based on the statistical tests of the 90-min prediction residuals of the filters. The unscented Kalman filter had the highest average F score of 85.9%, and the smallest average detection delay of 84.1%, with the average detection sensitivity of 82.6%, and average specificity of 91.0%.
AB - The purpose of this study is to compare the performance of three nonlinear filters in online drift detection of continuous glucose monitors. The nonlinear filters are the extended Kalman filter (EKF), the unscented Kalman filter (UKF), and the particle filter (PF). They are all based on a nonlinear model of the glucose-insulin dynamics in people with type 1 diabetes. Drift is modelled by a Gaussian random walk and is detected based on the statistical tests of the 90-min prediction residuals of the filters. The unscented Kalman filter had the highest average F score of 85.9%, and the smallest average detection delay of 84.1%, with the average detection sensitivity of 82.6%, and average specificity of 91.0%.
KW - Blood Chemical Analysis
KW - Blood Glucose
KW - Humans
KW - Models, Biological
KW - Nonlinear Dynamics
KW - Normal Distribution
KW - Signal Processing, Computer-Assisted
KW - Comparative Study
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
U2 - 10.1109/EMBC.2016.7591484
DO - 10.1109/EMBC.2016.7591484
M3 - Conference article
C2 - 28269054
SN - 2375-7477
VL - 2016
SP - 3507
EP - 3510
JO - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
JF - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
ER -