Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures

Keyphrases

• Excitotoxic 100%
• Kainic Acid 100%
• N-methyl-D-aspartate 100%
• Organotypic Brain Slice Culture 100%
• Neurotoxicity 57%
• Receptor Agonist 42%
• Glutamate Receptor Antagonists 42%
• AMPA Receptor (AMPAR) 42%
• Kainic Acid Receptors 42%
• Glutamate Receptors 28%
• High Concentration 28%
• Propionic Acid 28%
• EC50 28%
• Metabotropic Glutamate Receptor 5 (mGluR5) 28%
• 2-amino-3 28%
• Fascia Dentata 28%
• Slice Culture 28%
• Propidium Iodide Uptake 28%
• Hippocampal Slice Culture 28%
• N-methyl-D-aspartate Receptor (NMDAR) 14%
• Rank Order 14%
• Concentration-dependent 14%
• Best Model 14%
• Cellular Uptake 14%
• Methyl 14%
• Glutamate Decarboxylase 14%
• Neurodegeneration 14%
• Acid Activation 14%
• Hippocampal Neurons 14%
• Receptor Subunits 14%
• MK-801 14%
• Selective Agonist 14%
• GYKI 52466 14%
• Neuronal Damage 14%
• Concentration-response Curve 14%
• Decarboxylase Activity 14%
• Primary Neuronal Culture 14%
• Tert 14%
• Propidium Iodide 14%
• Isoxazole 14%
• Hippocampal Subfields 14%
• Glutamate Agonist 14%
• AMPA Excitotoxicity 14%
• N-methyl-D-aspartate Glutamate Receptor 14%
• Selective Concentration 14%

Neuroscience

• Aspartic Acid 100%
• Kainic Acid 100%
• AMPA 100%
• Alpha Amino 5 Tert Butyl 3 Hydroxy 4 Isoxazolepropionic Acid 100%
• Glutamate Receptor 55%
• Excitotoxicity 55%
• Receptor Agonists 33%
• Agonist 33%
• Propidium Iodide 33%
• AMPA Receptor 33%
• Kainate Receptor 33%
• Receptor Antagonist 22%
• Propionic Acid 22%
• Fascia Dentata 22%
• In Vivo 11%
• Glutamic Acid 11%
• Interneuron 11%
• Receptor Subunit 11%
• Nerve Cell Degeneration 11%
• Isoxazole 11%
• Glutamate Decarboxylase 11%
• NBQX 11%
• Carboxy-Lyases 11%

Pharmacology, Toxicology and Pharmaceutical Science

• Aspartic Acid 100%
• Kainic Acid 100%
• Alpha Amino 3 Hydroxy 5 Methyl 4 Isoxazolepropionic Acid 100%
• Alpha Amino 5 Tert Butyl 3 Hydroxy 4 Isoxazolepropionic Acid 100%
• Excitotoxicity 55%
• Glutamate Receptor Antagonist 33%
• Propidium Iodide 33%
• Glutamate Receptor Agonist 33%
• Kainic Acid Receptor 33%
• Propionic Acid 22%
• AMPA Receptor 22%
• Glutamate Receptor 11%
• Nerve Cell Degeneration 11%
• Receptor Subunit 11%
• Isoxazole 11%
• Glutamate Decarboxylase 11%
• Carboxylyase 11%
• AMPA Receptor Agonist 11%
• NBQX 11%