Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Comparison of Dual Energy X-ray Absorptiometry and Bioimpedance in Assessing Body Composition and Nutrition in Peritoneal Dialysis Patients

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Nut Consumption and Renal Function Among Women With a History of Gestational Diabetes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Importance of Differentiation Between Phosphorous and Phosphate

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Serum uric acid as a new player in the development of diabetic nephropathy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Decreased markers of bone turnover in children and adolescents with type 1 diabetes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Unaffected bone mineral density in Danish children and adolescents with type 1 diabetes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Bone turnover markers during the remission phase in children and adolescents with type 1 diabetes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVE: Peritoneal dialysis (PD) patients are characterized by protein malnutrition and muscle wasting. Reliable, easy, and cheap methods for evaluating nutrition are desirable. Three methods are commonly available: dual-energy X-ray absorptiometry (DXA), bioimpedance (BI), and subjective global assessment (SGA).The objective of the study was to compare the previously mentioned methods for assessment of body composition and nutritional status in PD patients.

DESIGN: The study is cross-sectional and consisted of 72 PD patients from a single center PD ambulatorium.

METHODS: Participants were measured twice by DXA, twice by BI, and once by SGA. Measurements included lean tissue mass (LTM), fat tissue mass (FT) and, for BI, overhydration (OH), intracellular water (ICW), and extracellular water (ECW). LTM and FT were indexed to body area (Lean Tissue Index [LTI] and Fat Tissue Index [FTI], respectively), and ICW for height (ICW/ht). We assessed conventional biochemical and clinical variables, using values for normal individuals as a reference.

RESULTS: There was good overall agreement between BI and DXA but considerable intra-individual variation (1 standard deviation: FT 5.7 kg; LTM 5.6 kg). Factors affecting the differences were FT, ICW, LTM, and ICW. Obesity (DXA 43%; BI 54%) and muscle wasting (BI 28%; SGA 53%) were common. Agreement between BI and SGA was poor. Thirty-eight percent of patients judged malnourished by SGA also had a low LTI; 23% with normal SGA had low LTI. SGA was closer related to LTI (BI) than LTI (DXA). Plasma albumin was correlated to LTI, FTI, and ICW/ht, and comorbidity to OH, clinical malnutrition, reduced FTI, but not LTI.

CONCLUSION: Agreement between DXA and BI was high on a population basis but not at an individual level. Obesity and muscle wasting were common in this population. OH might reduce DXA accuracy in PD patients. LTI and ICW may be useful measures to supplement SGA in assessing nutrition.

OriginalsprogEngelsk
TidsskriftJournal of Renal Nutrition
Vol/bind27
Udgave nummer5
Sider (fra-til)355-363
Antal sider9
ISSN1051-2276
DOI
StatusUdgivet - sep. 2017

ID: 52667105