Common TNF-alpha, IL-1 beta, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis

Kristine Marie Jessen; Sarah Bjerre Lindboe; Anncatrine Luisa Petersen; Jesper Eugen-Olsen; Thomas Benfield

doi:10.1186/1471-2334-7-108

Common TNF-alpha, IL-1 beta, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis

Kristine Marie Jessen
, Sarah Bjerre Lindboe
, Anncatrine Luisa Petersen
, Jesper Eugen-Olsen
, Thomas Benfield

60 Citationer (Scopus)

Abstract

Several studies have investigated single nucleotide polymorphisms (SNPs) in candidate genes associated with sepsis and septic shock with conflicting results. Only few studies have combined the analysis of multiple SNPs in the same population.

Originalsprog	Engelsk
Tidsskrift	BMC Infectious Disease
Vol/bind	18
Udgave nummer	7
Sider (fra-til)	108
DOI	https://doi.org/10.1186/1471-2334-7-108
Status	Udgivet - 2007

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10.1186/1471-2334-7-108

http://www.biomedcentral.com/content/pdf/1471-2334-7-108.pdf

Citationsformater

Common TNF-alpha, IL-1 beta, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis. / Jessen, Kristine Marie; Lindboe, Sarah Bjerre; Petersen, Anncatrine Luisa et al.
I: BMC Infectious Disease, Bind 18, Nr. 7, 2007, s. 108.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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title = "Common TNF-alpha, IL-1 beta, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis",

abstract = "Several studies have investigated single nucleotide polymorphisms (SNPs) in candidate genes associated with sepsis and septic shock with conflicting results. Only few studies have combined the analysis of multiple SNPs in the same population.",

keywords = "Aged, Aged, 80 and over, Antigens, CD14, Bacteremia, Cytokines, Female, Gram-Negative Bacteria, Gram-Negative Bacterial Infections, Humans, Interleukin-1beta, Male, Middle Aged, Plasminogen Activator Inhibitor 1, Polymorphism, Single Nucleotide, Receptors, Immunologic, Severity of Illness Index, Toll-Like Receptor 4, Tumor Necrosis Factor-alpha, Urokinase-Type Plasminogen Activator",

author = "Jessen, \{Kristine Marie\} and Lindboe, \{Sarah Bjerre\} and Petersen, \{Anncatrine Luisa\} and Jesper Eugen-Olsen and Thomas Benfield",

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doi = "10.1186/1471-2334-7-108",

language = "English",

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T1 - Common TNF-alpha, IL-1 beta, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis

AU - Jessen, Kristine Marie

AU - Lindboe, Sarah Bjerre

AU - Petersen, Anncatrine Luisa

AU - Eugen-Olsen, Jesper

AU - Benfield, Thomas

PY - 2007

Y1 - 2007

N2 - Several studies have investigated single nucleotide polymorphisms (SNPs) in candidate genes associated with sepsis and septic shock with conflicting results. Only few studies have combined the analysis of multiple SNPs in the same population.

AB - Several studies have investigated single nucleotide polymorphisms (SNPs) in candidate genes associated with sepsis and septic shock with conflicting results. Only few studies have combined the analysis of multiple SNPs in the same population.

KW - Aged

KW - Aged, 80 and over

KW - Antigens, CD14

KW - Bacteremia

KW - Cytokines

KW - Female

KW - Gram-Negative Bacteria

KW - Gram-Negative Bacterial Infections

KW - Humans

KW - Interleukin-1beta

KW - Male

KW - Middle Aged

KW - Plasminogen Activator Inhibitor 1

KW - Polymorphism, Single Nucleotide

KW - Receptors, Immunologic

KW - Severity of Illness Index

KW - Toll-Like Receptor 4

KW - Tumor Necrosis Factor-alpha

KW - Urokinase-Type Plasminogen Activator

U2 - 10.1186/1471-2334-7-108

DO - 10.1186/1471-2334-7-108

M3 - Journal article

C2 - 17877801

VL - 18

SP - 108

JO - BMC Infectious Disease

JF - BMC Infectious Disease

IS - 7

ER -

Common TNF-alpha, IL-1 beta, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis

Abstract

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