@article{8fc6445f137441d796ce891e5f019da9,
title = "Common and rare alleles in apolipoprotein B contribute to plasma levels of low-density lipoprotein cholesterol in the general population",
abstract = "We have previously shown that rare mutations in the apolipoprotein B gene (APOB) may result in not only severe hypercholesterolemia and ischemic heart disease but also hypocholesterolemia. Despite this, common single-nucleotide polymorphisms (SNPs) in APOB have not convincingly been demonstrated to affect low-density lipoprotein (LDL) cholesterol levels.",
keywords = "Adult, Aged, Aged, 80 and over, Alleles, Apolipoproteins B, Cholesterol, LDL, Female, Humans, Linkage Disequilibrium, Male, Middle Aged, Myocardial Infarction, Myocardial Ischemia, Polymorphism, Single Nucleotide, Prospective Studies",
author = "Marianne Benn and Stene, {Maria Charlotte Aslaug} and Nordestgaard, {B{\o}rge G} and Jensen, {Gorm B} and Rolf Steffensen and Anne Tybjaerg-Hansen",
year = "2008",
doi = "10.1210/jc.2007-1365",
language = "English",
volume = "93",
pages = "1038--45",
journal = "Journal of Clinical Endocrinology and Metabolism",
issn = "0021-972X",
publisher = "Endocrine Society",
number = "3",
}