TY - JOUR
T1 - Combined PET/MR imaging in neurology
T2 - MR-based attenuation correction implies a strong spatial bias when ignoring bone
AU - Andersen, Flemming Littrup
AU - Ladefoged, Claes Nøhr
AU - Beyer, Thomas
AU - Keller, Sune Høgild
AU - Hansen, Adam Espe
AU - Højgaard, Liselotte
AU - Kjær, Andreas
AU - Law, Ian
AU - Holm, Søren
N1 - © 2013 Elsevier Inc. All rights reserved.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Combined PET/MR systems have now become available for clinical use. Given the lack of integrated standard transmission (TX) sources in these systems, attenuation and scatter correction (AC) must be performed using the available MR-images. Since bone tissue cannot easily be accounted for during MR-AC, PET quantification can be biased, in particular, in the vicinity of the skull. Here, we assess PET quantification in PET/MR imaging of patients using phantoms and patient data.
AB - Combined PET/MR systems have now become available for clinical use. Given the lack of integrated standard transmission (TX) sources in these systems, attenuation and scatter correction (AC) must be performed using the available MR-images. Since bone tissue cannot easily be accounted for during MR-AC, PET quantification can be biased, in particular, in the vicinity of the skull. Here, we assess PET quantification in PET/MR imaging of patients using phantoms and patient data.
U2 - 10.1016/j.neuroimage.2013.08.042
DO - 10.1016/j.neuroimage.2013.08.042
M3 - Journal article
C2 - 23994317
VL - 84
SP - 206
EP - 216
JO - NeuroImage
JF - NeuroImage
SN - 1053-8119
ER -