Combined left and right ventricular volume determination by radionuclide angiocardiography using double bolus and equilibrium technique.

Bidragets oversatte titel: Combined left and right ventricular volume determination by radionuclide angiocardiography using double bolus and equilibrium technique.

K H Stokholm, M Stubgaard, J Møgelvang, O Henriksen

13 Citationer (Scopus)

Abstract

Eighteen patients with ischaemic heart disease were studied. Left and right ventricular volumes including cardiac output (forward flow) were determined by radionuclide angiocardiography using a double bolus and equilibrium technique. As reference, cardiac output was simultaneously measured by indicator dilution. The radionuclide technique comprised four steps: (1) a first-pass study of right ventricle; (2) a bolus study of left ventricle; (3) an equilibrium study of left ventricle; (4) determination of the distribution volume of red blood cells. Absolute volumes of left ventricle were determined from steps 2 + 3 + 4. Absolute volumes of right ventricle were calculated from stroke volume and right ventricular ejection fraction (EF) which in turn was determined from step 1 by creating composite systolic and composite diastolic images. There was an acceptable agreement between stroke volume determinations by radionuclide angiocardiography and indicator dilution (r = 0.74; P less than 0.001). Stroke volume determination by radionuclide was 83 +/- 20 ml (mean +/- SD) and by indicator dilution 84 +/- 20 ml with a difference of -1 +/- 15 ml (NS). Cardiac output determination by radionuclide was 5.24 +/- 1.37 l min-1 and by indicator dilution 5.28 +/- 1.23 l min-1 with a difference of -0.04 +/- 0.95 l min-1 (NS). Left ventricular EF was 0.44 +/- 0.14 and right ventricular EF 0.57 +/- 0.10. The intra-observer coefficient of variation for duplicate calculations of the radionuclide determinations was 5.5% for stroke volume, 2.5% for left ventricular EF and 4.8% for right ventricular EF.
Bidragets oversatte titelCombined left and right ventricular volume determination by radionuclide angiocardiography using double bolus and equilibrium technique.
OriginalsprogEngelsk
TidsskriftClinical physiology (Oxford, England)
Vol/bind10
Udgave nummer5
Sider (fra-til)475-488
Antal sider14
ISSN0144-5979
StatusUdgivet - 1990

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