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Combination of autoantibodies against different histone proteins influences complement-dependent phagocytosis of necrotic cell material by polymorphonuclear leukocytes in systemic lupus erythematosus

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  1. Early life body size, growth and risks of systemic lupus erythematosus - A large Danish observational cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Accrual of Atherosclerotic Vascular Events in a Multicenter Inception Systemic Lupus Erythematosus Cohort

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • Birgitta Gullstrand
  • Malin H Lefort
  • Helena Tydén
  • Andreas Jönsen
  • Christian Lood
  • Asa Johansson
  • Søren Jacobsen
  • Lennart Truedsson
  • Anders A Bengtsson
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Polymorphonuclear leukocytes (PMN) with autoantibody-coated engulfed necrotic cell material (NC) are frequently seen in systemic lupus erythematosus (SLE). We evaluated the roles of complement, different antihistone antibodies (anti-H ab), and oxidative burst in the phagocytosis of NC by PMN, as well as association to disease activity and clinical phenotype in SLE.
OriginalsprogEngelsk
TidsskriftJournal of Rheumatology
Vol/bind39
Udgave nummer8
Sider (fra-til)1619-27
Antal sider9
ISSN0315-162X
DOI
StatusUdgivet - 2012

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