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Udgivet

Cochlear Implantation After Radiotherapy of Vestibular Schwannomas

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Intracochlear Vestibular Schwannoma Presenting with Mixed Hearing Loss

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Neurotransmitter and neurotransmitter receptor expression in the saccule of the human vestibular system

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Assessing competence in cochlear implant surgery using the newly developed Cochlear Implant Surgery Assessment Tool

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Cochlear implantation in Branchiootorenal syndrome - case report and review of the literature

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  4. Vestibular Function in Pendred Syndrome: Intact High Frequency VOR and Saccular Hypersensitivity

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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BACKGROUND AND OBJECTIVES: Vestibular schwannomas (VS) frequently lead to ipsilateral sensorineural hearing loss (HL) as part of its natural history or as a result of treatment. Cochlear implantation represents a well-documented treatment of profound HL that cannot be treated adequately with a conventional hearing aid, thus being offered to selected VS patients. A functional cochlea and cochlear nerve are prerequisites for sound perception with a cochlear implant (CI). The potential impact of radiotherapy on these structures is thus an important issue for subsequent CI hearing outcomes. The objective of this article is to present a case and to review the existing literature on the outcomes of cochlear implantation in irradiated VS patients systematically.

METHODS: A systematic literature review using preferred reporting items for systematic reviews and meta-analyses was conducted. Medline was searched systematically. Papers reporting ipsilateral CI outcomes after radiotherapy of VS were included. Additionally, results of CI after stereotactic radiotherapy in a 54-year-old male with neurofibromatosis type 2 are presented.

RESULTS: A total of 14 papers (33 patients) fulfilled inclusion criteria. Moderate preoperative HL was found in 11 patients. Six had moderate to severe HL, whereas 16 had severe HL or total deafness. Postoperative hearing outcomes varied from poor in 27% of patients to excellent in 19%, with remaining cases lying in between (mean follow-up of 19 months). Most patients achieved improvement in hearing and quality of life.

CONCLUSION: Despite variation in the degree of hearing outcome, CI after radiotherapy of VS appears to be effective in the majority of cases, as more than 70% of patients have good or excellent outcomes within 1-2 years post-implantation. Subjective benefits are considerable, even in cases with relatively poor objective outcome.

OriginalsprogEngelsk
TidsskriftThe Journal of International Advanced Otology
Vol/bind17
Udgave nummer5
Sider (fra-til)452-460
Antal sider9
ISSN1308-7649
DOI
StatusUdgivet - sep. 2021

ID: 76237232