Clozapine Rechallenge After Major Adverse Effects: Clinical Guidelines Based on 259 Cases

Keyphrases

• Confidence Interval 100%
• Adverse Effects 100%
• Clinical Practice Guidelines 100%
• Rechallenge 100%
• Guideline-based 100%
• Clozapine Rechallenge 100%
• Clozapine 50%
• Myocarditis 50%
• Life-threatening 33%
• Neutropenia 33%
• Clinical Option 33%
• Neuroleptic Malignant Syndrome 33%
• Agranulocytosis 33%
• Pancreatitis 16%
• MEDLINE 16%
• Atrial Flutter 16%
• QT Prolongation 16%
• Cardiomyopathy 16%
• Treatment-resistant Schizophrenia 16%
• Renal Insufficiency 16%
• Cardiac Complications 16%
• Lower End 16%
• Successful Outcome 16%
• Eosinophilia 16%
• Return-to-baseline 16%
• Pericarditis 16%
• Gastrointestinal Hypomotility 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Adverse Event 100%
• Clozapine 100%
• Myocarditis 42%
• Neutropenia 28%
• Agranulocytosis 28%
• Neuroleptic Malignant Syndrome 28%
• Heart Atrium Flutter 14%
• Kidney Failure 14%
• Eosinophilia 14%
• Cardiomyopathy 14%
• Pancreatitis 14%
• Pericarditis 14%