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Region Hovedstaden - en del af Københavns Universitetshospital
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Clinical update on contact allergy

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Highlights in allergic contact dermatitis 2018/2019

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. The impact of common metal allergens in daily devices

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Allergen-specific immunotherapy and risk of autoimmune disease

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. The current state of recombinant allergens for immunotherapy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Causative exposures and temporal development of cobalt allergy in Denmark between 2002 and 2017

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Diagnostic workup of occupational allergic nickel dermatitis in a nurse with multiple nickel exposures

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Patch test reactivity to aluminium chambers

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Highlights in allergic contact dermatitis 2018/2019

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

PURPOSE OF REVIEW: The aim of this article is to review recent findings in contact allergy, regarding clinical research.

RECENT FINDINGS: The biocide methyldibromo glutaronitrile was identified to be an important sensitizer. Subsequently, it was banned from leave-on cosmetics in the European Union. Another group of important allergens that have been studied extensively included the fragrances oak moss absolute, isoeugenol, hydroxyisohexyl 3-cyclohexene carboxaldehyde and farnesol. A new fragrance mix II has been developed for standard testing, which includes the two latter compounds. Dose response studies have demonstrated broad individual variation of elicitation thresholds, dependent on the allergen concentration during induction, and other factors. Some unsuspected routes of exposure to allergens include oral, inhalational, connubial or airborne contact. Experimental studies provide a classification of newly introduced chemicals; increasingly, the local lymph node assay is supplementing and potentially replacing the guinea pig maximization test. Recent advances in occupational contact allergy include, for example, some attempts to improve diagnostics for epoxy resin and other plastic, glue, and cutting fluid components.

SUMMARY: Constant awareness for new allergens, confirmed by critical evaluation, standardization of patch test materials, and the identification of temporal patterns and subgroups at risk will improve both the diagnosis and prevention of allergic contact dermatitis.

OriginalsprogEngelsk
TidsskriftCurrent Opinion in Allergy and Clinical Immunology
Vol/bind5
Udgave nummer5
Sider (fra-til)429-36
Antal sider8
ISSN1528-4050
StatusUdgivet - okt. 2005

ID: 51611872