Clinical Presentation of Atopic Dermatitis by Filaggrin Gene Mutation Status during the First 7 Years of Life in a Prospective Cohort Study

Charlotte Giwercman Carson; Morten Arendt Rasmussen; Jacob P Thyssen; Torkil Menné; Hans Bisgaard

doi:10.1371/journal.pone.0048678

Clinical Presentation of Atopic Dermatitis by Filaggrin Gene Mutation Status during the First 7 Years of Life in a Prospective Cohort Study

Charlotte Giwercman Carson, Morten Arendt Rasmussen, Jacob P Thyssen, Torkil Menné, Hans Bisgaard

Afdeling for Allergi, Hud- og Kønssygdomme HGH

70 Citationer (Scopus)

Abstract

Filaggrin null mutations result in impaired skin barrier functions, increase the risk of early onset atopic dermatitis and lead to a more severe and chronic disease. We aimed to characterize the clinical presentation and course of atopic dermatitis associated with filaggrin mutations within the first 7 years of life.

Originalsprog	Engelsk
Tidsskrift	P L o S One
Vol/bind	7
Udgave nummer	11
Sider (fra-til)	e48678
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0048678
Status	Udgivet - 2012

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10.1371/journal.pone.0048678

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abstract = "Filaggrin null mutations result in impaired skin barrier functions, increase the risk of early onset atopic dermatitis and lead to a more severe and chronic disease. We aimed to characterize the clinical presentation and course of atopic dermatitis associated with filaggrin mutations within the first 7 years of life.",

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AU - Menné, Torkil

AU - Bisgaard, Hans

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AB - Filaggrin null mutations result in impaired skin barrier functions, increase the risk of early onset atopic dermatitis and lead to a more severe and chronic disease. We aimed to characterize the clinical presentation and course of atopic dermatitis associated with filaggrin mutations within the first 7 years of life.

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DO - 10.1371/journal.pone.0048678

M3 - Journal article

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Clinical Presentation of Atopic Dermatitis by Filaggrin Gene Mutation Status during the First 7 Years of Life in a Prospective Cohort Study

Abstract

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