Clearing and Masking Agents in Pretargeting Strategies

Markus Staudt*, Matthias M Herth

*Corresponding author af dette arbejde

Abstract

'Pretargeting' led to increased target-to-background ratios of nanomedicines in short timeframes. However, clearing or masking agents are needed to reach the full potential of pretargeted approaches. This review gives an overview of clearing and masking agents employed in pretargeting strategies in both preclinical and clinical settings and discusses how these agents work.

OriginalsprogEngelsk
Artikelnummer497
TidsskriftPharmaceuticals (Basel, Switzerland)
Vol/bind16
Udgave nummer4
ISSN1424-8247
DOI
StatusUdgivet - 27 mar. 2023

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