Cimetidinbehandling ved cancer ventriculi

H Tønnesen; U P Knigge; S Bülow; P Damm; K Fischerman; P Hesselfeldt; A Hjortrup; I K Pedersen; V M Pedersen; O J Siemssen

Cimetidinbehandling ved cancer ventriculi

H Tønnesen, U P Knigge, S Bülow, P Damm, K Fischerman, P Hesselfeldt, A Hjortrup, I K Pedersen, V M Pedersen, O J Siemssen

3 Citationer (Scopus)

Abstract

The effect of cimetidine treatment in cancer of the stomach was investigated in a double-blind, multicentre study comprising eight departments in Greater Copenhagen. Immediately after operation (or the decision not to operate) 181 patients were subdivided at random to treatment with a placebo or cimetidine in a dosage of 400 mg twice daily for two years or until death. Compliance control was carried out every third month. The mean survival in the cimetidine group (450 days, 1-1,826) was significantly longer (p = 0.02) than in the placebo group (316 days, 1-1,653).

Bidragets oversatte titel	Cimetidine treatment of stomach cancer
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	151
Udgave nummer	24
Sider (fra-til)	1549-51
Antal sider	3
ISSN	0041-5782
Status	Udgivet - 12 jun. 1989

Emneord

Adult
Aged
Cimetidine
Clinical Trials as Topic
Double-Blind Method
Female
Humans
Male
Middle Aged
Multicenter Studies as Topic
Stomach Neoplasms

Citationsformater

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title = "Cimetidinbehandling ved cancer ventriculi",

abstract = "The effect of cimetidine treatment in cancer of the stomach was investigated in a double-blind, multicentre study comprising eight departments in Greater Copenhagen. Immediately after operation (or the decision not to operate) 181 patients were subdivided at random to treatment with a placebo or cimetidine in a dosage of 400 mg twice daily for two years or until death. Compliance control was carried out every third month. The mean survival in the cimetidine group (450 days, 1-1,826) was significantly longer (p = 0.02) than in the placebo group (316 days, 1-1,653).",

keywords = "Adult, Aged, Cimetidine, Clinical Trials as Topic, Double-Blind Method, Female, Humans, Male, Middle Aged, Multicenter Studies as Topic, Stomach Neoplasms, Clinical Trial, English Abstract, Journal Article, Multicenter Study, Randomized Controlled Trial",

author = "H T{\o}nnesen and Knigge, {U P} and S B{\"u}low and P Damm and K Fischerman and P Hesselfeldt and A Hjortrup and Pedersen, {I K} and Pedersen, {V M} and Siemssen, {O J}",

year = "1989",

month = jun,

day = "12",

language = "Dansk",

volume = "151",

pages = "1549--51",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

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number = "24",

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TY - JOUR

T1 - Cimetidinbehandling ved cancer ventriculi

AU - Tønnesen, H

AU - Knigge, U P

AU - Bülow, S

AU - Damm, P

AU - Fischerman, K

AU - Hesselfeldt, P

AU - Hjortrup, A

AU - Pedersen, I K

AU - Pedersen, V M

AU - Siemssen, O J

PY - 1989/6/12

Y1 - 1989/6/12

N2 - The effect of cimetidine treatment in cancer of the stomach was investigated in a double-blind, multicentre study comprising eight departments in Greater Copenhagen. Immediately after operation (or the decision not to operate) 181 patients were subdivided at random to treatment with a placebo or cimetidine in a dosage of 400 mg twice daily for two years or until death. Compliance control was carried out every third month. The mean survival in the cimetidine group (450 days, 1-1,826) was significantly longer (p = 0.02) than in the placebo group (316 days, 1-1,653).

AB - The effect of cimetidine treatment in cancer of the stomach was investigated in a double-blind, multicentre study comprising eight departments in Greater Copenhagen. Immediately after operation (or the decision not to operate) 181 patients were subdivided at random to treatment with a placebo or cimetidine in a dosage of 400 mg twice daily for two years or until death. Compliance control was carried out every third month. The mean survival in the cimetidine group (450 days, 1-1,826) was significantly longer (p = 0.02) than in the placebo group (316 days, 1-1,653).

KW - Adult

KW - Aged

KW - Cimetidine

KW - Clinical Trials as Topic

KW - Double-Blind Method

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Multicenter Studies as Topic

KW - Stomach Neoplasms

KW - Clinical Trial

KW - English Abstract

KW - Journal Article

KW - Multicenter Study

KW - Randomized Controlled Trial

M3 - Tidsskriftartikel

C2 - 2675427

SN - 0041-5782

VL - 151

SP - 1549

EP - 1551

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 24

ER -

Cimetidinbehandling ved cancer ventriculi

Abstract

Emneord

Fingeraftryk

Citationsformater