Ciclosporin does not attenuate intracranial hypertension in rats with acute hyperammonaemia

Rikke Hebo Larsen; Mette S Kjær; Martin Eefsen; Fin Stolze Larsen; Peter Nissen Bjerring

doi:10.4254/wjh.v5.i9.513

Ciclosporin does not attenuate intracranial hypertension in rats with acute hyperammonaemia

Rikke Hebo Larsen, Mette S Kjær, Martin Eefsen, Fin Stolze Larsen, Peter Nissen Bjerring

7 Citationer (Scopus)

Abstract

To investigate the neuroprotective potential of ciclosporin during acute liver failure. We evaluated the effect of intrathecally administered ciclosporin on intracranial pressure, brain water content and aquaporin-4 expression in a rat model with acute hyperammonaemia.

Originalsprog	Engelsk
Tidsskrift	World Journal of Hepatology
Vol/bind	5
Udgave nummer	9
Sider (fra-til)	513-20
Antal sider	8
ISSN	1948-5182
DOI	https://doi.org/10.4254/wjh.v5.i9.513
Status	Udgivet - 27 sep. 2013

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title = "Ciclosporin does not attenuate intracranial hypertension in rats with acute hyperammonaemia",

abstract = "To investigate the neuroprotective potential of ciclosporin during acute liver failure. We evaluated the effect of intrathecally administered ciclosporin on intracranial pressure, brain water content and aquaporin-4 expression in a rat model with acute hyperammonaemia.",

author = "Larsen, \{Rikke Hebo\} and Kj{\ae}r, \{Mette S\} and Martin Eefsen and Larsen, \{Fin Stolze\} and Bjerring, \{Peter Nissen\}",

year = "2013",

month = sep,

day = "27",

doi = "10.4254/wjh.v5.i9.513",

language = "English",

volume = "5",

pages = "513--20",

journal = "World Journal of Hepatology",

issn = "1948-5182",

publisher = "Beijing Baishideng BioMed Scientific Co., Ltd",

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TY - JOUR

T1 - Ciclosporin does not attenuate intracranial hypertension in rats with acute hyperammonaemia

AU - Larsen, Rikke Hebo

AU - Kjær, Mette S

AU - Eefsen, Martin

AU - Larsen, Fin Stolze

AU - Bjerring, Peter Nissen

PY - 2013/9/27

Y1 - 2013/9/27

N2 - To investigate the neuroprotective potential of ciclosporin during acute liver failure. We evaluated the effect of intrathecally administered ciclosporin on intracranial pressure, brain water content and aquaporin-4 expression in a rat model with acute hyperammonaemia.

AB - To investigate the neuroprotective potential of ciclosporin during acute liver failure. We evaluated the effect of intrathecally administered ciclosporin on intracranial pressure, brain water content and aquaporin-4 expression in a rat model with acute hyperammonaemia.

UR - https://www.scopus.com/pages/publications/84885811118

U2 - 10.4254/wjh.v5.i9.513

DO - 10.4254/wjh.v5.i9.513

M3 - Journal article

C2 - 24073303

SN - 1948-5182

VL - 5

SP - 513

EP - 520

JO - World Journal of Hepatology

JF - World Journal of Hepatology

IS - 9

ER -

Ciclosporin does not attenuate intracranial hypertension in rats with acute hyperammonaemia

Abstract

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