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Chronologic order of appearance of immune-mediated inflammatory diseases relative to diagnosis of psoriasis

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Efficacy of a second interleukin 17 inhibitor in patients with psoriasis: A systematic review and meta-analysis

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  2. Real-world evidence of dupilumab efficacy and risk of adverse events: A systematic review and meta-analysis

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  3. Anti-TNF biosimilars in psoriasis: from scientific evidence to real-world experience

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

Vis graf over relationer

BACKGROUND: Psoriasis is a common inflammatory skin disease associated with several immune-mediated inflammatory diseases (IMIDs); however, little is known of the chronology of disease development.

OBJECTIVE: To investigate the chronology of IMIDs relative to psoriasis.

METHODS: We utilized routinely collected data from Danish nationwide administrative registries to examine the occurrence of IMIDs in patients with psoriasis (n = 10,923) and general population controls (n = 109,230).

RESULTS: Approximately 20% of patients with psoriasis developed ≥1 IMID, with a 5-fold increased risk compared with the general population. Most IMIDs were diagnosed before psoriasis, except for psoriatic arthritis. Psoriasis was significantly associated with having multiple IMIDs (odds ratio 15.2, 95% confidence interval 11.6-20.0). Human leukocyte antigen B27 positivity was significantly more frequent among psoriasis patients.

LIMITATIONS: Clinical measurements were unavailable.

CONCLUSION: IMIDs occur frequently in patients with psoriasis and most are diagnosed before psoriasis. The observed chronology might represent important mechanisms of disease development.

OriginalsprogEngelsk
TidsskriftJournal of the American Academy of Dermatology
Vol/bind81
Udgave nummer6
Sider (fra-til)1283-1291
Antal sider9
ISSN0190-9622
DOI
StatusUdgivet - dec. 2019

Bibliografisk note

Copyright © 2019 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

ID: 58985984